Evidence map›Paper›PMID 34083772›Full record

ArticleNature nanotechnology2021

An antiviral trap made of protein nanofibrils and iron oxyhydroxide nanoparticles.

Archana Palika, Antonius Armanious, Akram Rahimi, Chiara Medaglia, Matteo Gasbarri, Stephan Handschin, Antonella Rossi, Marie O Pohl, Idoia Busnadiego, Christian Gübeli and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature nanotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Remediation of Metal Oxide Nanotoxicity with a Functional Amyloid.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  8. Tapered chiral nanoparticles as broad-spectrum thermally stable antivirals for SARS-CoV-2 variants.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Amyloid-Based Albumin Hydrogels.Advanced healthcare materials · 2023
    Article
  14. Interfacial Electrostatic Self-Assembly of Amyloid Fibrils into Multifunctional Protein Films.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Archana PalikaDepartment of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
Antonius ArmaniousDepartment of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-8809-4659
Akram RahimiDepartment of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
Chiara MedagliaDepartment of Microbiology and Molecular Medicine, University of Geneva, Geneva, Switzerland.
Matteo GasbarriInstitute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-8469-5369
Stephan HandschinDepartment of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
Antonella RossiDepartment of Chemical and Geological Science, University of Cagliari, Cagliari, Italy.ORCID http://orcid.org/0000-0002-5151-2634
Marie O PohlInstitute of Medical Virology, University of Zurich, Zurich, Switzerland.
Idoia BusnadiegoInstitute of Medical Virology, University of Zurich, Zurich, Switzerland.
Christian GübeliDepartment of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
Ravi B AnjanappaDepartment of Biology, ETH Zurich, Zurich, Switzerland.
Sreenath BolisettyDepartment of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
Mohammad PeydayeshDepartment of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-6265-3811
Silke StertzInstitute of Medical Virology, University of Zurich, Zurich, Switzerland.
Benjamin G HaleInstitute of Medical Virology, University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-3891-9480
Caroline TapparelDepartment of Microbiology and Molecular Medicine, University of Geneva, Geneva, Switzerland.
Francesco StellacciInstitute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-4635-6080
Raffaele MezzengaDepartment of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. raffaele.mezzenga@hest.ethz.ch.ORCID http://orcid.org/0000-0002-5739-2610

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimizing the spread of viruses in the environment is the first defence line when fighting outbreaks and pandemics, but the current COVID-19 pandemic demonstrates how difficult this is on a global scale, particularly in a sustainable and environmentally friendly way. Here we introduce and develop a sustainable and biodegradable antiviral filtration membrane composed of amyloid nanofibrils made from food-grade milk proteins and iron oxyhydroxide nanoparticles synthesized in situ from iron salts by simple pH tuning. Thus, all the membrane components are made of environmentally friendly, non-toxic and widely available materials. The membrane has outstanding efficacy against a broad range of viruses, which include enveloped, non-enveloped, airborne and waterborne viruses, such as SARS-CoV-2, H1N1 (the influenza A virus strain responsible for the swine flu pandemic in 2009) and enterovirus 71 (a non-enveloped virus resistant to harsh conditions, such as highly acidic pH), which highlights a possible role in fighting the current and future viral outbreaks and pandemics.

Indexed as

Micropore FiltersAmyloidAntiviral AgentsFerric CompoundsHumansLactoglobulinsNanoparticlesVirusesVirus InactivationWater PurificationAmyloidAntiviral AgentsFerric Compoundsferric hydroxideLactoglobulins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.