Evidence map›Paper›PMID 34083757›Full record

ArticleCommunications biology2021

3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme.

Melisa Lázaro, Roberto Melero, Charlotte Huet, Jorge P López-Alonso, Sandra Delgado, Alexandra Dodu, Eduardo M Bruch, Luciano A Abriata, Pedro M Alzari, Mikel Valle and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Melisa LázaroCenter for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801 A, Derio, Spain.
Roberto MeleroCentro Nacional de Biotecnología, CNB-CSIC, Darwin 3, Madrid, Spain.
Charlotte HuetUnité de Microbiologie Structurale, Institut Pasteur, CNRS UMR 3528, Université de Paris, 25 rue du Docteur Roux, Paris, France.
Jorge P López-AlonsoCenter for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801 A, Derio, Spain.ORCID 0000-0003-2081-2607
Sandra DelgadoCenter for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801 A, Derio, Spain.
Alexandra DoduCenter for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801 A, Derio, Spain.
Eduardo M BruchIntegrated Structural Biology Department, IGBMC, 1 Rue Laurent Fries, Illkirch, France.
Luciano A AbriataLaboratory for Biomolecular Modeling, School of Life Sciences, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.ORCID 0000-0003-3087-8677
Pedro M AlzariUnité de Microbiologie Structurale, Institut Pasteur, CNRS UMR 3528, Université de Paris, 25 rue du Docteur Roux, Paris, France.ORCID 0000-0002-4233-1903
Mikel ValleCenter for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801 A, Derio, Spain. mvalle@cicbiogune.es.ORCID 0000-0001-8268-6912
María-Natalia LisaUnité de Microbiologie Structurale, Institut Pasteur, CNRS UMR 3528, Université de Paris, 25 rue du Docteur Roux, Paris, France. lisa@ibr-conicet.gov.ar.ORCID 0000-0001-9630-8090
CIC bioGUNE · ESCentre National de la Recherche Scientifique · FRCentro Nacional de Biotecnología · ESSIB Swiss Institute of Bioinformatics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutamate dehydrogenases (GDHs) are widespread metabolic enzymes that play key roles in nitrogen homeostasis. Large glutamate dehydrogenases composed of 180 kDa subunits (L-GDHs

Indexed as

Bacterial ProteinsCatalytic DomainCryoelectron MicroscopyCrystallography, X-RayGlutamate DehydrogenaseKineticsModels, MolecularMycobacterium smegmatisProtein BindingProtein DomainsProtein MultimerizationRecombinant ProteinsBacterial ProteinsGlutamate DehydrogenaseRecombinant Proteins

Identifiers

PMID34083757
PMCPMC8175468
OpenAlexW3165366681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.