Evidence map›Paper›PMID 34083750›Full record

ArticleTurkish journal of obstetrics and gynecology2021

Perinatal outcomes of high-dose vitamin D administration in the last trimester

Gülin Karacan Küçükali, Melikşah Keskin, Şenay Savaş Erdeve, Semra Çetinkaya

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of obstetrics and gynecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Too much vitamin D? a drug safety review.Reviews in endocrine & metabolic disorders · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Nephrocalcinosis in children who received high-dose vitamin D.Pediatric nephrology (Berlin, Germany) · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gülin Karacan KüçükaliUniversity of Health Sciences Turkey, Dr. Sami Ulus Maternity and Children's Research and Training Hospital, Clinic of Pediatric Endocrinology, Ankara, TurkeyORCID 0000-0001-7506-1711
Melikşah KeskinUniversity of Health Sciences Turkey, Dr. Sami Ulus Maternity and Children's Research and Training Hospital, Clinic of Pediatric Endocrinology, Ankara, TurkeyORCID 0000-0002-2713-3618
Şenay Savaş ErdeveUniversity of Health Sciences Turkey, Dr. Sami Ulus Maternity and Children's Research and Training Hospital, Clinic of Pediatric Endocrinology, Ankara, TurkeyORCID 0000-0002-4164-5089
Semra ÇetinkayaUniversity of Health Sciences Turkey, Dr. Sami Ulus Maternity and Children's Research and Training Hospital, Clinic of Pediatric Endocrinology, Ankara, TurkeyORCID 0000-0003-3974-2872
Ministry of Health · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, interest in the evaluation of vitamin D levels and the possible outcomes of their deficiency during pregnancy has increased. However, there is no consensus on when to start vitamin D supplementation, its duration, dosage, and the optimum level during pregnancy. The toxicity of vitamin D is as important as its deficiency. From the history of a 5-day-old male baby who was investigated for hypercalcemia, it was learned that the mother took 300,000 IU vitamin D-five ampoules/oral at 30 weeks of gestation every other day. The infant was born prematurely, postpartum bradycardia required positive pressure ventilation, and his hypercalcemia lasted approximately 4 months despite treatment. Maternal excessive and inappropriate use of vitamin D can cause preterm labor and severe hypercalcemia, which is a life-threatening complication in the neonatal period. This case is presented to draw attention to the negative effects of maternal high-dose vitamin D during pregnancy.

Indexed as

25 (OH) vitamin DHypercalcemianeonatal outcomesvitamin D intoxication

Identifiers

PMID34083750
PMCPMC8191325
OpenAlexW3164693998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.