Evidence map›Paper›PMID 34083747›Full record

ArticleMucosal immunology2021

T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet.

Jessica L Barnes, Maximilian W Plank, Kelly Asquith, Steven Maltby, Lorena R Sabino, Gerard E Kaiko, Alyssa Lochrin, Jay C Horvat, Jemma R Mayall, Richard Y Kim and 5 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Hybrid lineages of CD4Frontiers in immunology · 2024
    Review
  4. Article
  5. Review
  6. From thymus to tissues and tumors: A review of T-cell biology.The Journal of allergy and clinical immunology · 2023
    Review
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Jessica L BarnesPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia. Jessica.Barnes@newcastle.edu.au.
Maximilian W PlankPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Kelly AsquithPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Steven MaltbyPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Lorena R SabinoPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Gerard E KaikoPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Alyssa LochrinPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Jay C HorvatPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Jemma R MayallPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Richard Y KimPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Philip M HansbroPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Simon KeelyHunter Medical Research Institute, New Lambton Heights, NSW, Australia.
Gabrielle T BelzThe Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, VIC, Australia.
Hock L TayPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia.
Paul S FosterPriority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia. Paul.Foster@newcastle.edu.au.
University of Newcastle Australia · AUHunter Medical Research Institute · AUAbbotsford Veterinary Clinic · CACentenary Institute · AUUniversity of Melbourne · AUUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4

Indexed as

AnimalsBacterial InfectionsCell DifferentiationDisease Models, AnimalDisease SusceptibilityGene Expression RegulationHost-Pathogen InteractionsImmunophenotypingInterleukin-17Interleukin-22InterleukinsMiceMice, KnockoutMice, TransgenicT-bet Transcription FactorT-Box Domain ProteinsInterleukin-17Interleukin-22InterleukinsT-bet Transcription FactorT-Box Domain Proteins

Identifiers

PMID34083747
OpenAlexW3165013340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.