Evidence map›Paper›PMID 34083718›Full record

Observational studyScientific reports2021

Potential adverse drug events and its predictors among hospitalized patients at medical center in Ethiopia: a prospective observational study.

Tamiru Sahilu, Mestawet Getachew, Tsegaye Melaku, Tadesse Sheleme, Duresa Abu, Tesfu Zewdu

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. High alert medications off the radar: A systematic review.Exploratory research in clinical and social pharmacy · 2025
    Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tamiru SahiluDepartment of Pharmacy, College of Health Science, Assosa University, Assosa, Ethiopia. tamepfsa@gmail.com.
Mestawet GetachewDepartment of Clinical Pharmacy, School of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia.
Tsegaye MelakuDepartment of Clinical Pharmacy, School of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia.
Tadesse ShelemeDepartment of Pharmacy, College of Public Health and Medical Science, Mettu University, Metu Zuria, Ethiopia.
Duresa AbuDepartment of Pharmacy, College of Health Science, Assosa University, Assosa, Ethiopia.
Tesfu ZewduDepartment of Nursing, College of Health Science, Assosa University, Assosa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Potential adverse drug event (PADE) is a medication error with the potential to cause associate degree injury however that does not cause any injury, either due to specific circumstances, chance, or as a result of the error being intercepted and corrected. This study aimed to assess the incidence, contributing factors, predictors, severity, and preventability of PADEs among hospitalized adult patients at Jimma Medical Center. A prospective observational study was conducted among hospitalized adult patients at a tertiary hospital in Ethiopia. Logistic regression was performed to identify factors predicting PADE occurrence. P-value < 0.05 was considered for statistical significance. A total of 319 patients were included. About 50.5% of them were females. The mean ± SD age of the participants was 43 ± 17.6 years. Ninety-four PADEs were identified. Number of medications (adjusted OR = 5.12; 95% CI: 2.01-13.05; p = 0.001), anticoagulants (adjusted OR = 2.51; 95% CI: 1.22-5.19; p = 0.013), anti-seizures (adjusted OR = 21.96; 95% CI: 6.57-73.39; p < 0.0001), anti-tuberculosis (adjusted OR = 2.2; 95% CI: 1.002-4.59, p = 0.049), and Elixhauser comorbidity Index ≤ 15 (adjusted OR = 6.24; 95% CI: 1.48-26.25, p = 0.013) were independent predictors of PADEs occurrence. About one-third of patients admitted to the hospital experienced PADEs.

Indexed as

HospitalizationTertiary Care CentersAdultAgedAged, 80 and overDisease ManagementDrug-Related Side Effects and Adverse ReactionsEthiopiaFemaleHumansIncidenceMaleMiddle AgedProspective StudiesPublic Health SurveillanceRisk Factors

Identifiers

PMID34083718
PMCPMC8175752

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.