ArticleScientific reports2021
Susceptibility of anurans, lizards, and fish to infection with Dracunculus species larvae and implications for their roles as paratenic hosts.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 12 citations in OpenAlex.
- Flubendazole reduces emerging Dracunculus medinensis in dogs in Chad: Results from a two-year study.PLoS neglected tropical diseases · 2026Article
- Flubendazole 2.0: Designing a large field trial in dogs for a challenging setting.PLoS neglected tropical diseases · 2026Article
- Dracunculus sp. PantanalBr Infection in Florida Panthers and Bobcat, Florida, USA.Emerging infectious diseases · 2026Article
- Evaluating wildlife community composition around villages with varying Guinea worm (International journal for parasitology. Parasites and wildlife · 2025Article
- Slaying the Serpent: A Research Agenda to Expand Intervention Development and Accelerate Guinea Worm Eradication Efforts.The American journal of tropical medicine and hygiene · 2024Article
- Otterly diverse - A high diversity ofInternational journal for parasitology. Parasites and wildlife · 2024Article
- A new dracunculus species (Nematoda: Dracunculoidea) in neotropical otters (International journal for parasitology. Parasites and wildlife · 2023Article
- Range of metastrongylids (superfamily Metastrongyloidea) of public health and veterinary concern present in livers of the endemic lizard Gallotia galloti of Tenerife, Canary Islands, Spain.Parasites & vectors · 2023Article
- Development and validation of a quantitative PCR for the detection of Guinea worm (Dracunculus medinensis).PLoS neglected tropical diseases · 2022Article
- Dracunculiasis Eradication: End-Stage Challenges.The American journal of tropical medicine and hygiene · 2022Article
- Effects of Temephos (Abate®), Spinosad (Natular®), and Diflubenzuron on the Survival of Cyclopoid Copepods.The American journal of tropical medicine and hygiene · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dracunculus spp. are parasitic nematodes that infect numerous species of mammals and reptiles. The life cycles of Dracunculus species are complex, and unknowns remain regarding the role of paratenic and transport hosts in transmission to definitive hosts. We had two primary objectives: to assess the susceptibility of several species of anurans, lizards, and fish as paratenic hosts for Dracunculus species, and to determine the long-term persistence of Dracunculus infections in African clawed frogs (Xenopus laevis). Animals were orally exposed to copepods infected with infectious third-stage larvae (L3s) of either Dracunculus insignis or D. medinensis. Dracunculus L3s were recovered from four anuran species, two lizard species, and one fish species, demonstrating that Dracunculus can infect tissues of a diversity of species. In long-term persistence trials, D. medinensis L3s were recovered from African clawed frogs tissues up to 58 days post-infection, and D. insignis L3s were recovered up to 244 days post-infection. Our findings regarding the susceptibility of novel species of frogs, lizards, and fish to infection with Dracunculus nematodes, and long-term persistence of L3s in paratenic hosts, address pressing knowledge gaps regarding Dracunculus infection in paratenic hosts and may guide future research regarding the transmission of Dracunculus to definitive mammalian hosts.
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