Evidence map›Paper›PMID 34083626›Full record

ArticleScientific reports2021

Connectivity adaptations in dopaminergic systems define the brain maturity of investors.

Elena Ortiz-Teran, Ibai Diez, Jorge Sepulcre, Joaquin Lopez-Pascual, Tomas Ortiz

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Elena Ortiz-TeranGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, USA. ortizterane@gmail.com.ORCID 0000-0001-5020-4894
Ibai DiezGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, USA.ORCID 0000-0001-5769-0178
Jorge SepulcreGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, USA.ORCID 0000-0002-4199-2304
Joaquin Lopez-PascualDepartamento de Economía de la Empresa, Facultad de Ciencias Jurídicas y Sociales, Universidad Rey Juan Carlos, 28032, Madrid, Spain.ORCID 0000-0002-6236-9853
Tomas OrtizDepartamento de Medicina Legal, Psiquiatría y Patología, Facultad de Medicina, Universidad Complutense de Madrid, 28040, Madrid, Spain.ORCID 0000-0002-0527-5869
Harvard University · USUniversidad Complutense de Madrid · ESUniversidad Rey Juan Carlos · ES

Funding

Genetic Profiles of the Spatiotemporal Causality of Tau and Amyloid in the Elderly BrainR01AG061445 · NIA · YALE UNIVERSITY · PI SEPULCRE, JORGE · 2019 to 2023
$1.9M
Sensory and Motor Streams in Preclinical and Clinical Stages of Alzheimer's DiseaseR01AG061811 · NIA · YALE UNIVERSITY · PI SEPULCRE, JORGE · 2019 to 2023
$1.7M
NIA NIH HHS R01 AG061445NIA NIH HHS R01 AG061811
6 · The paper itself

Abstract

Investment decisions rely on perceptions from external stimuli along with the integration of inner brain-body signals, all of which are shaped by experience. As experience is capable of molding both the structure and function of the human brain, we have used a novel neuroimaging connectomic-genetic approach to investigate the influence of investment work experience on brain anatomy. We found that senior investors display higher gray matter volume and increased structural brain connectivity in dopamine-related pathways, as well as a set of genes functionally associated with adrenaline and noradrenaline biosynthesis (SLC6A3, TH and SLC18A2), which is seemingly involved in reward processing and bodily stress responses during financial trading. These results suggest the key role of catecholamines in the way senior investors harness their emotions while raising bodily awareness as they grow in investment maturity.

Indexed as

Decision MakingInvestmentsAdultBrainBrain MappingConnectomeDopamineDopamine Plasma Membrane Transport ProteinsFemaleGene Expression ProfilingGene Expression RegulationHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedDopamineDopamine Plasma Membrane Transport Proteins

Identifiers

PMID34083626
PMCPMC8175592
OpenAlexW3163965895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.