Evidence map›Paper›PMID 34083579›Full record

ArticleScientific reports2021

Robust diagnostic classification via Q-learning.

Victor Ardulov, Victor R Martinez, Krishna Somandepalli, Shuting Zheng, Emma Salzman, Catherine Lord, Somer Bishop, Shrikanth Narayanan

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Victor ArdulovUniversity of Southern California, Los Angeles, USA. ardulov@usc.edu.
Victor R MartinezUniversity of Southern California, Los Angeles, USA.
Krishna SomandepalliUniversity of Southern California, Los Angeles, USA.
Shuting ZhengUniversity of California San Francisco, San Francisco, USA.
Emma SalzmanUniversity of California San Francisco, San Francisco, USA.
Catherine LordUniversity of California Los Angeles, Los Angeles, USA.
Somer BishopUniversity of California San Francisco, San Francisco, USA.
Shrikanth NarayananUniversity of Southern California, Los Angeles, USA.

Funding

Development of a standardized measure of social-communication abilities for children with neurodevelopmental disordersR01HD093012 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BISHOP, SOMER L. · 2017 to 2022
$3.2M
National Institute of Child Health and Human Development 1R01HD093012-01NICHD NIH HHS R01 HD093012
6 · The paper itself

Abstract

Machine learning (ML) models have demonstrated the power of utilizing clinical instruments to provide tools for domain experts in gaining additional insights toward complex clinical diagnoses. In this context these tools desire two additional properties: interpretability, being able to audit and understand the decision function, and robustness, being able to assign the correct label in spite of missing or noisy inputs. This work formulates diagnostic classification as a decision-making process and utilizes Q-learning to build classifiers that meet the aforementioned desired criteria. As an exemplary task, we simulate the process of differentiating Autism Spectrum Disorder from Attention Deficit-Hyperactivity Disorder in verbal school aged children. This application highlights how reinforcement learning frameworks can be utilized to train more robust classifiers by jointly learning to maximize diagnostic accuracy while minimizing the amount of information required.

Indexed as

Decision Support Systems, ClinicalMachine LearningSoftwareAlgorithmsAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderClinical Decision-MakingHumansModels, Theoretical

Identifiers

PMID34083579
PMCPMC8175431

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.