ArticleScientific reports2021
Age-sex population adjusted analysis of disease severity in epidemics as a tool to devise public health policies for COVID-19.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Non parametric differential network analysis: a tool for unveiling specific molecular signatures.BMC bioinformatics · 2024Article
- Understanding complex systems through differential causal networks.Scientific reports · 2024Article
- Current and future directions in network biology.Bioinformatics advances · 2024Article
- Investigating the effects of vaccine on COVID-19 disease propagation using a Bayesian approach.Scientific reports · 2023Article
- COVID-19 activity risk calculator as a gamified public health intervention tool.Scientific reports · 2023Article
- Analysis of age-dependent gene-expression in human tissues for studying diabetes comorbidities.Scientific reports · 2023Article
- Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia.The Journal of experimental medicine · 2023Article
- COVID-19-related stress, exercise, and oral health-related quality of life among community-dwelling older adults who participated in the CHEER Iwamizawa project, Japan.Scientific reports · 2022Article
- The Impact of Demographic, Clinical Characteristics and the Various COVID-19 Variant Types on All-Cause Mortality: A Case-Series Retrospective Study.Diseases (Basel, Switzerland) · 2022Article
- Circulating Illness and Changes in Thermometer Use Behavior: Series of Cross-sectional Analyses.JMIR formative research · 2022Article
- Potential of Microneedle Systems for COVID-19 Vaccination: Current Trends and Challenges.Pharmaceutics · 2022Review
- Article
- COVID-19 Disease Burden Related to Social Vulnerability and Comorbidities: Challenges to Tuberculosis Control.International journal of environmental research and public health · 2022Article
- Identifying multimorbidity profiles associated with COVID-19 severity in chronic patients using network analysis in the PRECOVID Study.Scientific reports · 2022Observational
- Analysis of immunization time, amplitude, and adverse events of seven different vaccines against SARS-CoV-2 across four different countries.Frontiers in immunology · 2022Observational
- Significance of hematologic abnormalities in COVID-19 severity among infected patients in Lagos, Nigeria.Bulletin of the National Research Centre · 2022Article
- Using data from a private provider of telemedicine to assess the severity of the early 2021 Covid-19 wave in Brazil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022Article
- Association Between Sex Hormone Levels and Clinical Outcomes in Patients With COVID-19 Admitted to Hospital: An Observational, Retrospective, Cohort Study.Frontiers in immunology · 2022Observational
- Exploiting the molecular basis of age and gender differences in outcomes of SARS-CoV-2 infections.Computational and structural biotechnology journal · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Governments continue to update social intervention strategies to contain COVID-19 infections. However, investigation of COVID-19 severity indicators across the population might help to design more precise strategies, balancing the need to keep people safe and to reduce the socio-economic burden of generalized restriction precedures. Here, we propose a method for age-sex population-adjusted analysis of disease severity in epidemics that has the advantage to use simple and repeatable variables, which are daily or weekly available. This allows to monitor the effect of public health policies in short term, and to repeat these calculations over time to surveille epidemic dynamics and impact. Our method can help to define a risk-categorization of likeliness to develop a severe COVID-19 disease which requires intensive care or is indicative of a higher risk of dying. Indeed, analysis of suitable open-access COVID-19 data in three European countries indicates that individuals in the 0-40 age interval and females under 60 are significantly less likely to develop a severe condition and die, whereas males equal or above 60 are more likely at risk of severe disease and death. Hence, a combination of age-adaptive and sex-balanced guidelines for social interventions could represent key public health management tools for policymakers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.