Evidence map›Paper›PMID 34083437›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The

Kun Tan, Matthew E Kim, Hye-Won Song, David Skarbrevik, Eric Babajanian, Tracy A Bedrosian, Fred H Gage, Miles F Wilkinson

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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  14. TheProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kun TanDepartment of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0002-8567-7795
Matthew E KimDepartment of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California San Diego, La Jolla, CA 92093.
Hye-Won SongDepartment of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California San Diego, La Jolla, CA 92093.
David SkarbrevikDepartment of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California San Diego, La Jolla, CA 92093.
Eric BabajanianDepartment of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California San Diego, La Jolla, CA 92093.
Tracy A BedrosianLaboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037.
Fred H GageLaboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037.ORCID 0000-0002-0938-4106
Miles F WilkinsonDepartment of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California San Diego, La Jolla, CA 92093; mfwilkinson@health.ucsd.edu.
University of California San Diego · USSalk Institute for Biological Studies · US

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Reuben Shaw · 1985 to 2026
$82.8M
Spermatogonial Stem Cell Establishment and RegulationR01GM119128 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TAN, KUN, WILKINSON, MILES FROME · 2016 to 2025
$3.6M
NCI NIH HHS P30 CA014195NIGMS NIH HHS R01 GM119128
6 · The paper itself

Abstract

Transposable elements (TEs) are mobile sequences that engender widespread mutations and thus are a major hazard that must be silenced. The most abundant active class of TEs in mammalian genomes is long interspersed element class 1 (

Indexed as

Multigene FamilyAnimalsDNA Transposable ElementsGene Expression RegulationGenes, X-LinkedGerm CellsHEK293 CellsHomeodomain ProteinsHumansLong Interspersed Nucleotide ElementsMaleMiceMice, Inbred C57BLSpermatogenesisTranscription FactorsDNA Transposable ElementsHomeodomain ProteinsRHOXF2 protein, humanTranscription FactorsLINE1piRNAPiwil2RHOX10transposon

Identifiers

PMID34083437
PMCPMC8201764
OpenAlexW3165002252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.