Evidence map›Paper›PMID 34083350›Full record

ArticleBMJ open2021

Characterising the long-term clinical outcomes of 1190 hospitalised patients with COVID-19 in New York City: a retrospective case series.

Sherif M Shoucri, Lawrence Purpura, Clare DeLaurentis, Matthew A Adan, Deborah A Theodore, Alexandria Lauren Irace, Shelief Y Robbins-Juarez, Apurva M Khedagi, Daniel Letchford, Amro A Harb and 20 more

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. SARS-CoV-2 post-acute sequelae in previously hospitalised patients: systematic literature review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  2. Pooled it
  3. Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022
    Pooled it
  4. Prevalence of post-acute COVID-19 syndrome symptoms at different follow-up periods: a systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Pooled it
  5. Article
  6. Article
  7. Long COVID syndrome: An unfolding enigma.The Indian journal of medical research · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Sherif M ShoucriMedicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA sms2319@cumc.columbia.edu.ORCID 0000-0002-6290-2320
Lawrence PurpuraMedicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA.
Clare DeLaurentisMedicine, Columbia University Irving Medical Center, New York City, New York, USA.
Matthew A AdanColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.ORCID 0000-0003-2515-8982
Deborah A TheodoreMedicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA.
Alexandria Lauren IraceColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.ORCID 0000-0003-4758-3146
Shelief Y Robbins-JuarezColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Apurva M KhedagiColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Daniel LetchfordColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Amro A HarbColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Lillian M ZerihunColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Kate E LeeColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.ORCID 0000-0002-0171-7121
Karen GambinaColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Max C LauringColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Noah ChenColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Colin P SperringColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Sanket S MehtaColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Ellen L MyersColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Hueyjong ShihColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Michael G ArgenzianoColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.ORCID 0000-0003-3374-9037
Samuel L BruceColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Cody L SlaterColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Jonathan R TiaoColumbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Karthik NatarajanBiomedical Informatics, Columbia University Irving Medical Center, New York City, New York, USA.
George HripcsakBiomedical Informatics, Columbia University Irving Medical Center, New York City, New York, USA.
Ruijun ChenBiomedical Informatics, Columbia University Irving Medical Center, New York City, New York, USA.
Michael T YinMedicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA.
Magdalena E SobieszczykMedicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA.
Delivette CastorMedicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA.
Jason E ZuckerMedicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA.

Funding

Columbia Partnership for Prevention and Control of HIV/AIDS Clinical Trials UnitUM1AI069470 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAGDALENA ELZBIETA SOBIESZCZYK · 2012 to 2026
$44.8M
Columbia Collaborative HIV/AIDS Clinical Trials UnitU01AI069470 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HAMMER, SCOTT M · 2007 to 2011
$15.4M
DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASESR01LM006910 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HRIPCSAK, GEORGE M · 2000 to 2023
$10.6M
Multidisciplinary Training in Translational Gastrointestinal and Liver ResearchT32DK083256 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Timothy Cragin Wang · 2009 to 2026
$5.5M
Columbia Integrated Training Program in Infectious Diseases ResearchT32AI100852 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAGDALENA ELZBIETA SOBIESZCZYK, Anne-Catrin Uhlemann · 2013 to 2026
$2.2M
Harnessing Bioinformatics for HIV Prevention: Understanding Persistence in Comprehensive HIV Prevention ServicesK23AI150378 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZUCKER, JASON · 2020 to 2024
$960k
NIAID NIH HHS K23 AI150378NIAID NIH HHS L30 AI133789NIAID NIH HHS T32 AI100852NIAID NIH HHS U01 AI069470NIAID NIH HHS UM1 AI069470NIDDK NIH HHS T32 DK083256NLM NIH HHS R01 LM006910
6 · The paper itself

Abstract

objectiveTo characterise the long-term outcomes of patients with COVID-19 admitted to a large New York City medical centre at 3 and 6 months after hospitalisation and describe their healthcare usage, symptoms, morbidity and mortality.

designRetrospective cohort through manual chart review of the electronic medical record.

settingNewYork-Presbyterian/Columbia University Irving Medical Center, a quaternary care academic medical centre in New York City.

participantsThe first 1190 consecutive patients with symptoms of COVID-19 who presented to the hospital for care between 1 March and 8 April 2020 and tested positive for SARS-CoV-2 on reverse transcriptase PCR assay.

main outcome measuresType and frequency of follow-up encounters, self-reported symptoms, morbidity and mortality at 3 and 6 months after presentation, respectively; patient disposition information prior to admission, at discharge, and at 3 and 6 months after hospital presentation.

resultsOf the 1190 reviewed patients, 929 survived their initial hospitalisation and 261 died. Among survivors, 570 had follow-up encounters (488 at 3 months and 364 at 6 months). An additional 33 patients died in the follow-up period. In the first 3 months after admission, most encounters were telehealth visits (59%). Cardiopulmonary symptoms (35.7% and 28%), especially dyspnoea (22.1% and 15.9%), were the most common reported symptoms at 3-month and 6-month encounters, respectively. Additionally, a large number of patients reported generalised (26.4%) or neuropsychiatric (24.2%) symptoms 6 months after hospitalisation. Patients with severe COVID-19 were more likely to have reduced mobility, reduced independence or a new dialysis requirement in the 6 months after hospitalisation.

conclusionsPatients hospitalised with SARS-CoV-2 infection reported persistent symptoms up to 6 months after diagnosis. These results highlight the long-term morbidity of COVID-19 and its burden on patients and healthcare resources.

Indexed as

COVID-19HospitalizationHumansNew York CityRetrospective StudiesSARS-CoV-2COVID-19infectious diseasesvirology

Identifiers

PMID34083350
PMCPMC8182750

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.