Evidence map›Paper›PMID 34083342›Full record

ArticleBMJ open2021

Provision of critical care for the elderly in Europe: a retrospective comparison of national healthcare frameworks in intensive care units.

Bernhard Wernly, Michael Beil, Raphael Romano Bruno, Stephan Binnebössel, Malte Kelm, Sviri Sigal, Peter Vernon van Heerden, Ariane Boumendil, Antonio Artigas, Maurizio Cecconi and 16 more

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03134807 completednot on this map

The Very Old Intensive Care Patient: A Multinational Prospective Observation Study

TypeobservationalSponsorUniversity of BergenRan2016 to 2017Enrolled5,132ConditionsCritical Illness, Old Age, Debility, SurvivalArmsObservation prospective
NCT03370692 completednot on this map

Development and Validation of a Prognostic Score in the Very Old ICU Patients (≥80 Years)

TypeobservationalSponsorUniversity of BergenRan2018 to 2019Enrolled3,900ConditionsAged, 80 and Over, Critical CareArmsCognitive assesment, Frailty assessment
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 18 institutions in 16 countries.

Bernhard WernlyDepartment of Anaesthesiology, Perioperative Medicine and Intensive Care Medicine, Paracelsus Medical University Salzburg, Salzburg, Austria.ORCID 0000-0003-4024-0220
Michael BeilDepartment of Medical Intensive Care, Hadassah University Medical Center, Jerusalem, Israel.
Raphael Romano BrunoDivision of Cardiology, Pulmonology, and Vascular Medicine, University Hospital Dusseldorf, Dusseldorf, Germany.ORCID 0000-0003-3776-3530
Stephan BinnebösselDivision of Cardiology, Pulmonology, and Vascular Medicine, University Hospital Dusseldorf, Dusseldorf, Germany.
Malte KelmDivision of Cardiology, Pulmonology, and Vascular Medicine, University Hospital Dusseldorf, Dusseldorf, Germany.ORCID 0000-0001-5834-2757
Sviri SigalDepartment of Medical Intensive Care, Hadassah University Medical Center, Jerusalem, Israel.
Peter Vernon van HeerdenGeneral Intensive Care, Hadassah Medical Center, Jerusalem, Israel.
Ariane Boumendilservice de réanimation médicale, Hôpital Saint-Antoine, Paris, France.
Antonio ArtigasDepatment of Intensive Care Medicine, Autonomous University of Barcelona, Sabadell, Catalonia, Spain.
Maurizio CecconiDepartment of Anaesthesia, Humanitas University, Milan, Italy.
Brian MarshCritical Care Medicine, Mater Misericordiae University Hospital, Dublin, Ireland.
Rui MorenoDepartment of Intensive Care, UCINC, Hospital de São José, Centro Hospitalar de Lisboa Central, EPE, Lisbon, Portugal.
Sandra OeyenDepartment of Intensive Care, University of Ghent, Ghent, Belgium.
Bernardo Bollen PintoDepartment of Acute Medicine, Geneva University Hospitals, Geneve, Switzerland.
Wojciech SzczeklikDepartment of Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.ORCID 0000-0002-1349-1123
Susannah LeaverGeneral Intensive Care, Research Lead Critical Care Directorate St George's Hospital, London, UK.
Sten Mikael WaltherDepartment of Medicine and Health Sciences, Faculty of Health Sciences, Linköping University, Division of Cardiovascular Medicine, Linköping, Sweden.
Joerg C SchefoldIntensive Care Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.
Michael JoannidisDivision o Intensive Care and Emergency Medicine, Dept. Medicine, Medizinische Universitat Innsbruck, Innsbruck, Tirol, Austria.
Jesper FjølnerDepartment of Intensive Care, Aarhus Universitet, Aarhus, Denmark.
Tilemachos ZafeiridisDepartment of Critical Care, General University Hospital of Larissa, Larissa, Thessaly, Greece.
Dylan de LangeDepartment of Intensive Care Medicine, Utrecht University, Utrecht, The Netherlands.
Bertrand GuidetService de Réanimation, Service de Réanimation Médicale Hôpital Saint-Antoine, Paris, France.
Hans FlaattenDepartment of Anesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway.
Christian JungDivision of Cardiology, Pulmonology, and Vascular Medicine, University Hospital Dusseldorf, Dusseldorf, Germany christian.jung@med.uni-duesseldorf.de.
VIP2 study group
Düsseldorf University Hospital · DEHadassah Medical Center · ILSorbonne Université · FRAarhus University · DKHaukeland University Hospital · NOHumanitas University · ITInnsbruck Medical University · ATJagiellonian University · PLLinköping University · SEMater Misericordiae University Hospital · IEParacelsus Medical University · ATSt George's Hospital · GBUnidade Local de Saúde de São José · PTUniversitat Autònoma de Barcelona · ESUniversity Hospital of Bern · CHUniversity Hospital of Larissa · GRUniversity of Geneva · CHUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn Europe, there is a distinction between two different healthcare organisation systems, the tax-based healthcare system (THS) and the social health insurance system (SHI). Our aim was to investigate whether the characteristics, treatment and mortality of older, critically ill patients in the intensive care unit (ICU) differed between THS and SHI.

settingICUs in 16 European countries.

participantsIn total, 7817 critically ill older (≥80 years) patients were included in this study, 4941 in THS and 2876 in the SHI systems. PRIMARY AND SECONDARY OUTCOMES MEASURES: We chose generalised estimation equations with robust standard errors to produce population average adjusted OR (aOR). We adjusted for patient-specific variables, health economic data, including gross domestic product (GDP) and human development index (HDI), and treatment strategies.

resultsIn SHI systems, there were higher rates of frail patients (Clinical Frailty Scale>4; 46% vs 41%; p<0.001), longer length of ICU stays (90±162 vs 72±134 hours; p<0.001) and increased levels of organ support. The ICU mortality (aOR 1.50, 95% CI 1.09 to 2.06; p=0.01) was consistently higher in the SHI; however, the 30-day mortality (aOR 0.89, 95% CI 0.66 to 1.21; p=0.47) was similar between THS and SHI. In a sensitivity analysis stratifying for the health economic data, the 30-day mortality was higher in SHI, in low GDP per capita (aOR 2.17, 95% CI 1.42 to 3.58) and low HDI (aOR 1.22, 95% CI 1.64 to 2.20) settings.

conclusionsThe 30-day mortality was similar in both systems. Patients in SHI were older, sicker and frailer at baseline, which could be interpreted as a sign for a more liberal admission policy in SHI. We believe that the observed trend towards ICU excess mortality in SHI results mainly from a more liberal admission policy and an increase in treatment limitations. TRIAL REGISTRATION NUMBERS: NCT03134807 and NCT03370692.

Indexed as

Critical CareIntensive Care UnitsAgedCritical IllnessDelivery of Health CareEuropeHospital MortalityHumansLength of StayRetrospective Studiesadult intensive & critical caregeriatric medicinepublic health

Identifiers

PMID34083342
PMCPMC8183284
OpenAlexW3164963848

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.