Evidence map›Paper›PMID 34083190›Full record

ArticleBMJ case reports2021

Extreme hypercalcaemia caused by immobilisation due to acute spinal cord injury.

Jesse Marc Tettero, Elmer van Eeghen, Albertus Jozef Kooter

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jesse Marc TetteroHematology, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Elmer van EeghenInternal Medicine, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Albertus Jozef KooterInternal Medicine, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands JKooter@amsterdamumc.nl.
Amsterdam University Medical Centers · NLAmsterdam UMC Location VUmc · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypercalcaemia due to immobilisation is an uncommon diagnosis and requires extensive evaluation to rule out common causes of hypercalcaemia such as primary hyperparathyroidism and malignancy.We report an unusual case of profound hypercalcaemia due to immobilisation in a young man due to acute spinal cord ischaemia, leading to paraplegia. Other causes of hypercalcaemia were ruled out and elevated bone turnover markers supported our hypothesis. Conventional treatment with intravenous fluids, bisphosphonates and diuretics was insufficient. Subcutaneous calcitonin lowered the plasma calcium acutely and was continued for 8 weeks. Subsequent normocalcaemia was sustained for 2 years.

Indexed as

Bone Density Conservation AgentsHypercalcemiaSpinal Cord InjuriesCalcitoninCalciumDiphosphonatesHumansMaleBone Density Conservation AgentsCalcitoninCalciumDiphosphonatescalcium and boneendocrinology

Identifiers

PMID34083190
PMCPMC8174501
OpenAlexW3164757792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.