ArticleBiotechnology for biofuels2021
Extracellular riboflavin induces anaerobic biofilm formation in Shewanella oneidensis.
Article in Biotechnology for biofuels, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 54 citations in OpenAlex.
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- Spatially resolved charge-transfer kinetics at the quantum dot-microbe interface using fluorescence lifetime imaging microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Single-cell phenotyping of extracellular electron transfer via microdroplet encapsulation.Applied and environmental microbiology · 2025Article
- Overlap and differences between the inward and outward electron transfer pathways in Shewanella oneidensis.FEMS microbiology letters · 2025Article
- Comparative analysis of the influence of BpfA and BpfG on biofilm development and current density in Shewanella oneidensis under oxic, fumarate- and anode-respiring conditions.Scientific reports · 2024Article
- Single-Cell Phenotyping of Extracellular Electron Transfer via Microdroplet Encapsulation.bioRxiv : the preprint server for biology · 2024Article
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- Genome-Wide Computational Prediction and Analysis of Noncoding RNAs inMicroorganisms · 2024Article
- Promastigote EPS secretion and haptomonad biofilm formation as evolutionary adaptations of trypanosomatid parasites for colonizing honeybee hosts.NPJ biofilms and microbiomes · 2024Article
- Genomic characterization of rare earth binding by Shewanella oneidensis.Scientific reports · 2023Article
- Microbe-Anode Interactions: Comparing the impact of genetic and material engineering approaches to improve the performance of microbial electrochemical systems (MES).Microbial biotechnology · 2023Review
- Highly efficient multiplex base editing: One-shot deactivation of eight genes inSynthetic and systems biotechnology · 2023Article
- EngineeringSynthetic and systems biotechnology · 2022Article
- Coproduction and enhancement of electricity and biobutanol using adsorption carrier solid-state fermentation.Biotechnology for biofuels and bioproducts · 2022Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundSome microorganisms can respire with extracellular electron acceptors using an extended electron transport chain to the cell surface. This process can be applied in bioelectrochemical systems in which the organisms produce an electrical current by respiring with an anode as electron acceptor. These organisms apply flavin molecules as cofactors to facilitate one-electron transfer catalyzed by the terminal reductases and in some cases as endogenous electron shuttles.
resultsIn the model organism Shewanella oneidensis, riboflavin production and excretion trigger a specific biofilm formation response that is initiated at a specific threshold concentration, similar to canonical quorum-sensing molecules. Riboflavin-mediated messaging is based on the overexpression of the gene encoding the putrescine decarboxylase speC which leads to posttranscriptional overproduction of proteins involved in biofilm formation. Using a model of growth-dependent riboflavin production under batch and biofilm growth conditions, the number of cells necessary to produce the threshold concentration per time was deduced. Furthermore, our results indicate that specific retention of riboflavin in the biofilm matrix leads to localized concentrations, which by far exceed the necessary threshold value.
conclusionThis study describes a new quorum-sensing mechanism in S. oneidensis. Biofilm formation of S. oneidensis is induced by low concentrations of riboflavin resulting in an upregulation of the ornithine-decarboxylase speC. The results can be applied for the development of strains catalyzing increased current densities in bioelectrochemical systems.
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