ArticleBMC medical informatics and decision making2021
Examining the effect of explanation on satisfaction and trust in AI diagnostic systems.
Article in BMC medical informatics and decision making, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 70 citations in OpenAlex.
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- Defining operational safety in clinical artificial intelligence systems.NPJ digital medicine · 2026Article
- Investigating Whether AI Will Replace Human Physicians and Understanding the Interplay of the Source of Consultation, Health-Related Stigma, and Explanations of Diagnoses on Patients' Evaluations of Medical Consultations: Randomized Factorial Experiment.Journal of medical Internet research · 2025Article
- Leveraging artificial intelligence to reduce diagnostic errors in emergency medicine: Challenges, opportunities, and future directions.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025Review
- Prioritizing Trust in Podiatrists' Preference for AI in Supportive Roles Over Diagnostic Roles in Health Care: Qualitative Interview and Focus Group Study.JMIR human factors · 2025Article
- Current Applications, Challenges, and Future Directions of Artificial Intelligence in Emergency Medicine: A Narrative Review.Archives of academic emergency medicine · 2025Article
- Expert gaze as a usability indicator of medical AI decision support systems: a preliminary study.NPJ digital medicine · 2024Article
- Concept-based reasoning in medical imaging.International journal of computer assisted radiology and surgery · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArtificial Intelligence has the potential to revolutionize healthcare, and it is increasingly being deployed to support and assist medical diagnosis. One potential application of AI is as the first point of contact for patients, replacing initial diagnoses prior to sending a patient to a specialist, allowing health care professionals to focus on more challenging and critical aspects of treatment. But for AI systems to succeed in this role, it will not be enough for them to merely provide accurate diagnoses and predictions. In addition, it will need to provide explanations (both to physicians and patients) about why the diagnoses are made. Without this, accurate and correct diagnoses and treatments might otherwise be ignored or rejected.
methodIt is important to evaluate the effectiveness of these explanations and understand the relative effectiveness of different kinds of explanations. In this paper, we examine this problem across two simulation experiments. For the first experiment, we tested a re-diagnosis scenario to understand the effect of local and global explanations. In a second simulation experiment, we implemented different forms of explanation in a similar diagnosis scenario.
resultsResults show that explanation helps improve satisfaction measures during the critical re-diagnosis period but had little effect before re-diagnosis (when initial treatment was taking place) or after (when an alternate diagnosis resolved the case successfully). Furthermore, initial "global" explanations about the process had no impact on immediate satisfaction but improved later judgments of understanding about the AI. Results of the second experiment show that visual and example-based explanations integrated with rationales had a significantly better impact on patient satisfaction and trust than no explanations, or with text-based rationales alone. As in Experiment 1, these explanations had their effect primarily on immediate measures of satisfaction during the re-diagnosis crisis, with little advantage prior to re-diagnosis or once the diagnosis was successfully resolved.
conclusionThese two studies help us to draw several conclusions about how patient-facing explanatory diagnostic systems may succeed or fail. Based on these studies and the review of the literature, we will provide some design recommendations for the explanations offered for AI systems in the healthcare domain.
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