ArticleBMC cardiovascular disorders2021
Native T1 mapping and extracellular volume fraction for differentiation of myocardial diseases from normal CMR controls in routine clinical practice.
Article in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quality of science and reporting for radiomics in cardiac magnetic resonance imaging studies: a systematic review.European radiology · 2022Pooled it
- T1 Mapping In Differentiating Healthy And Pathological Myocardium.Anatolian journal of cardiology · 2026Article
- Feasibility of using synthetic myocardial extracellular volume fraction derived from blood CT attenuation for the differentiation of heart failure.The international journal of cardiovascular imaging · 2026Article
- Case Report: Multimodality imaging of a primary right ventricular fibroma in an asymptomatic adult.Frontiers in medicine · 2026Article
- Demographically informed models for improving synthetic haematocrit and extracellular volume estimation in cardiac computed tomography.European heart journal. Imaging methods and practice · 2026Article
- Prediction of histopathological grade in gastric cancer using dual energy CT-derived synthetic extracellular volume fraction.Frontiers in oncology · 2025Article
- Improvement of Quantification of Myocardial Synthetic ECV with Second-Generation Deep Learning Reconstruction.Journal of cardiovascular development and disease · 2024Article
- Next-Generation Cardiac Magnetic Resonance Imaging Techniques for Characterization of Myocardial Disease.Current treatment options in cardiovascular medicine · 2024Article
- A comparative study of synthetic and venous hematocrit for calculating cardiovascular magnetic resonance-derived extracellular volume.The international journal of cardiovascular imaging · 2024Article
- Cardiac amyloidosis and aortic stenosis: a state-of-the-art review.European heart journal open · 2023Review
- T1 values and extracellular volume fraction in asymptomatic subjects: variations in left ventricular segments and correlation with cardiovascular risk factors.Scientific reports · 2022Article
- Segmental strain for scar detection in acute myocardial infarcts and in follow-up exams using non-contrast CMR cine sequences.BMC cardiovascular disorders · 2022Article
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4 authors.
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Abstract
backgroundThis study aimed to determine native T1 and extracellular volume fraction (ECV) in distinct types of myocardial disease, including amyloidosis, dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), myocarditis and coronary artery disease (CAD), compared to controls.
methodsWe retrospectively enrolled patients with distinct types of myocardial disease, CAD patients, and control group (no known heart disease and negative CMR study) who underwent 3.0 Tesla CMR with routine T1 mapping. The region of interest (ROI) was drawn in the myocardium of the mid left ventricular (LV) short axis slice and at the interventricular septum of mid LV slice. ECV was calculated by actual hematocrit (Hct) and synthetic Hct. T1 mapping and ECV was compared between myocardial disease and controls, and between CAD and controls. Diagnostic yield and cut-off values were assessed.
resultsA total of 1188 patients were enrolled. The average T1 values in the control group were 1304 ± 42 ms at septum, and 1294 ± 37 ms at mid LV slice. The average T1 values in patients with myocardial disease and CAD were significantly higher than in controls (1441 ± 72, 1349 ± 59, 1345 ± 59, 1355 ± 56, and 1328 ± 54 ms for septum of amyloidosis, DCM, HCM, myocarditis, and CAD). Native T1 of the mid LV level and ECV at septum and mid LV with actual and synthetic Hct of patients with myocardial disease or CAD were significantly higher than in controls.
conclusionsAlthough native T1 and ECV of patients with cardiomyopathy and CAD were significantly higher than controls, the values overlapped. The greatest clinical utilization was found for the amyloidosis group.
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