ArticleMicrobial biotechnology2021
Endophytes isolated from Panax notoginseng converted ginsenosides.
Article in Microbial biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Genomic Insights Into Biocontrol and Plant Growth-Promoting Mechanisms of Paenibacillus maysiensis LHJ6 Against Root Rot in Panax notoginseng.Plant, cell & environment · 2026Article
- Rhizosphere fungal generalists drive plant metabolic adaptability via regulating soil micronutrient availability.Environmental microbiome · 2025Article
- Reconsidering the ecological effect of seed endophytes in building plant microbial environments: lessons from a Chinese medicinal plant Panax notoginseng.Environmental microbiome · 2025Article
- Effect of rhizosphere soil microbial communities and environmental factors on growth and the active ingredients of Angelica sinensis in Gansu Province, China.Folia microbiologica · 2025Article
- Soil microorganism colonization influenced the growth and secondary metabolite accumulation of Bletilla striata (Thunb.) Rchb. F.BMC microbiology · 2025Article
- Endophytic Bacteria Enterobacter cloacae PN7 Promotes Biosynthesis and Accumulation of Saponins in Panax notoginseng.Current microbiology · 2024Article
- Root microbiome of Panax ginseng in comparison with three other medicinal plants in the families of Araliaceae and Apiaceae.Scientific reports · 2024Article
- Stochasticity-dominated rare fungal endophytes contribute to coexistence stability and saponin accumulation in Panax species.Environmental microbiome · 2024Article
- Review
- Endophytic fungi of Panax sokpayensis produce bioactive ginsenoside Compound K in flask fermentation.Scientific reports · 2024Article
- Revealing Medicinal Constituents ofMolecules (Basel, Switzerland) · 2024Article
- Endophytic bacteria: a sustainable strategy for enhancing medicinal plant cultivation and preserving microbial diversity.Frontiers in microbiology · 2024Review
- Temporal patterns of endophytic microbial heterogeneity across distinct ecological compartments within theFrontiers in microbiology · 2024Article
- Article
- Plants and endophytes interaction: a "secret wedlock" for sustainable biosynthesis of pharmaceutically important secondary metabolites.Microbial cell factories · 2023Review
- Optimization of Fermentation Conditions and Product Identification of a Saponin-Producing Endophytic Fungus.Microorganisms · 2023Article
- Compound K Production: Achievements and Perspectives.Life (Basel, Switzerland) · 2023Review
- Diversity and correlation analysis of endophytes and metabolites of Panax quinquefolius L. in various tissues.BMC plant biology · 2023Article
- Culturable endophytic fungi community structure isolated from Codonopsis pilosula roots and effect of season and geographic location on their structures.BMC microbiology · 2023Article
- Ginsenosides and Biotic Stress Responses of Ginseng.Plants (Basel, Switzerland) · 2023Review
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12 authors.
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Abstract
Endophytes may participate in the conversion of metabolites within medicinal plants, influencing the efficacy of host. However, the distribution of endophytes within medicinal plants P. notoginseng and how it contributes to the conversion of saponins are not well understood. Here, we determined the distribution of saponins and endophytes within P. notoginseng compartments and further confirm the saponin conversion by endophytes. We found metabolites showed compartment specificity within P. notoginseng. Potential saponin biomarkers, such as Rb1, Rg1, Re, Rc and Rd, were obtained. Endophytic diversity, composition and co-occurrence networks also showed compartment specificity, and bacterial alpha diversity values were highest in root compartment, consistently decreased in the stem and leaf compartments, whereas those of fungi showed the opposite trend. Potential bacterial biomarkers, such as Rhizobium, Bacillus, Pseudomonas, Enterobacter, Klebsiella, Pantoea and fungal biomarkers Phoma, Epicoccum, Xylariales, were also obtained. Endophytes related to saponin contents were found by Spearman correlation analysis, and further verification experiments showed that Enterobacter chengduensis could convert ginsenoside Rg1 to F1 at a rate of 13.24%; Trichoderma koningii could convert ginsenoside Rb1 to Rd at a rate of 40.00% and to Rg3 at a rate of 32.31%; Penicillium chermesinum could convert ginsenoside Rb1 to Rd at a rate of 74.24%.
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