Evidence map›Paper›PMID 34081619›Full record

ArticleAging2021

Risk of arterial stiffness according to metabolically healthy obese phenotype: a combined cross-sectional and longitudinal study in kailuan cohort.

Anxin Wang, Yu Wang, Yingting Zuo, Xue Tian, Shuohua Chen, Yihan Ma, Xu Han, Shouling Wu, Xingquan Zhao

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Anxin WangChina National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yu WangChina National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yingting ZuoDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.
Xue TianDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.
Shuohua ChenDepartment of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan, China.
Yihan MaDepartment of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan, China.
Xu HanDepartment of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan, China.
Shouling WuDepartment of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan, China.
Xingquan ZhaoChina National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
North China University of Science and Technology · CNCapital Medical University · CNBeijing Tian Tan Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aim to investigate the risk of incident arterial stiffness according to metabolically healthy obese (MHO) phenotype in Chinese population. 37,180 participants with at least one-time measurement of branchial-ankle pulse wave velocity (baPWV) were included in the cross-sectional analysis, and 16,236 participants with repeated measurement of baPWV during the follow-ups were included in the longitudinal study. Cross-classification of body mass index (BMI) categories and metabolic health status created six groups. Linear and logistic regression analyses were used. The results of cross-sectional and longitudinal investigation were essentially the same, as the abnormality of baPWV increased with BMI categories in metabolically healthy participants, while the increasing tendency disappeared in metabolically unhealthy participants. A 1.4-fold, 2.2-fold increased risk for the new occurrence of arterial stiffness were documented in MHO and metabolically unhealthy obese participants compared to metabolically healthy normal-weight controls in the fully adjusted model. Further stratified analysis showed that metabolic health status was an interaction factor between BMI and arterial stiffness in all study populations (

Indexed as

Ankle Brachial IndexBody Mass IndexConfidence IntervalsCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedObesityOdds RatioPhenotypePulse Wave AnalysisRisk FactorsVascular Stiffnessarterial stiffnessbaPWVmetabolic syndromeobesity

Identifiers

PMID34081619
PMCPMC8221340
OpenAlexW3113060181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.