Evidence map›Paper›PMID 34081334›Full record

ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2021

SARS-CoV-2 infection and cancer: Evidence for and against a role of SARS-CoV-2 in cancer onset.

Aureliano Stingi, Luca Cirillo

Abstract readReviewVideo-Audio Media
In one paragraph

Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
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  11. Article
  12. Deciphering the Relationship between SARS-CoV-2 and Cancer.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Review
  15. Coronavirus disease 2019 and lung cancer: where are we?Exploration of targeted anti-tumor therapy · 2023
    Review
  16. Article
  17. Article
  18. Review
  19. SARS-CoV2 Infection and Comorbidities, Role in Oncogenesis.Asian Pacific journal of cancer prevention : APJCP · 2022
    Article
  20. Immune mechanisms in cancer patients that lead to poor outcomes of SARS-CoV-2 infection.Translational research : the journal of laboratory and clinical medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aureliano StingiDepartment of Cellular Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Luca CirilloCancer Biology Division, The Institute of Cancer Research, London, UK.

Funding

IGE3 PhD Salary AwardSNF Early Postoc Mobility
6 · The paper itself

Abstract

Despite huge efforts towards understanding the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis, little is known about the long-term consequences of the disease. Here, we critically review existing literature about oncogenesis as a potential long-term effect of SARS-CoV-2 infection. Like other viral infections, SARS-CoV-2 may promote cancer onset by inhibiting tumor suppressor genes. We conclude that, although unlikely, such hypothesis cannot be excluded a priori and we delineate an experimental approach to address it. Also see the video abstract here: https://youtu.be/TBUTDSLR7vY.

Indexed as

COVID-19NeoplasmsVirus DiseasesHumansSARS-CoV-2cancerCOVID-19oncogenic virusesSARS-CoV-2

Identifiers

PMID34081334
PMCPMC8209829

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.