Evidence map›Paper›PMID 34081255›Full record

SynthesisJournal of cardiovascular translational research2022

Predictors of Mortality in Patients Treated with Veno-Arterial ECMO for Cardiogenic Shock Complicating Acute Myocardial Infarction: a Systematic Review and Meta-Analysis.

Shahmir Sohail, Eddy Fan, Farid Foroutan, Heather J Ross, Filio Billia, Ana Carolina Alba

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of cardiovascular translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Extracorporeal Membrane Oxygenation.Respiratory care · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shahmir SohailDivision of Cardiology, Peter Munk Cardiac Center, University of Toronto, Toronto, ON, Canada. shahmir.sohail@mail.utoronto.ca.ORCID 0000-0001-7826-0257
Eddy FanToronto General Hospital, Toronto, ON, Canada.
Farid ForoutanDivision of Cardiology, Peter Munk Cardiac Center, University of Toronto, Toronto, ON, Canada.
Heather J RossDivision of Cardiology, Peter Munk Cardiac Center, University of Toronto, Toronto, ON, Canada.
Filio BilliaDivision of Cardiology, Peter Munk Cardiac Center, University of Toronto, Toronto, ON, Canada.
Ana Carolina AlbaDivision of Cardiology, Peter Munk Cardiac Center, University of Toronto, Toronto, ON, Canada.
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMortality for patients on veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock (CS) complicating acute myocardial infarction (AMI) remains high. This meta-analysis aims to identify factors that predict higher risk of mortality after VA-ECMO for AMI.

methodsWe meta-analyzed mortality after VA-ECMO for CS complicating AMI and the effect of factors from systematically selected studies published after 2009.

results72 studies (10,276 patients) were included with a pooled mortality estimate of 58 %. With high confidence in estimates, failure to achieve TIMI III flow and left main culprit were identified as factors associated with higher mortality. With low-moderate confidence, older age, high BMI, renal dysfunction, increasing lactate, prothrombin activity < 50%, VA-ECMO implantation after revascularization, and non-shockable ventricular arrythmias were identified as factors associated with mortality.

conclusionThese results provide clinicians with a framework for selecting patients for VA-ECMO for CS complicating AMI.

Indexed as

Extracorporeal Membrane OxygenationMyocardial InfarctionHospital MortalityHumansRetrospective StudiesShock, CardiogenicCardiogenic shockMortalityMyocardial infarctionVA-ECMO

Identifiers

PMID34081255
OpenAlexW3164242993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.