Evidence map›Paper›PMID 34081222›Full record

ReviewCurrent cardiology reports2021

Sex-Specific Plaque Signature: Uniqueness of Atherosclerosis in Women.

Anum Minhas, Ilton Cubero Salazar, Brigitte Kazzi, Allison G Hays, Andrew D Choi, Armin Arbab-Zadeh, Erin D Michos

Open access · greenAbstract readReview
In one paragraph

Review in Current cardiology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  15. Gender Medicine in Clinical Radiology Practice.Journal of personalized medicine · 2023
    Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anum MinhasDivision of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Ilton Cubero SalazarDivision of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Brigitte KazziDivision of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Allison G HaysDivision of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Andrew D ChoiDivision of Cardiology, Department of Radiology, George Washington University School of Medicine, Washington, DC, USA.
Armin Arbab-ZadehDivision of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Erin D MichosDivision of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA. edonnell@jhmi.edu.ORCID http://orcid.org/0000-0002-5547-5084
Johns Hopkins University · USGeorge Washington University · US

Funding

CARDIOVASCULAR EPIDEMIOLOGY INSTITUTIONAL TRAININGT32HL007024 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Elizabeth Selvin · 1985 to 2026
$17.5M
NHLBI NIH HHS T32 HL007024
6 · The paper itself

Abstract

purpose of reviewCardiovascular disease is a leading cause of morbidity and mortality in both men and women, although there are notable differences in presentation between men and women. Atherosclerosis remains the predominant driver of coronary heart disease in both sexes; however, sex differences in atherosclerosis should be investigated further to understand clinical manifestations between men and women. RECENT

findingsThere are sex differences in the prevalence, progression, and prognostic impact of atherosclerosis. Furthermore, developing evidence demonstrates unique differences in atherosclerotic plaque characteristics between men and women on both noninvasive and invasive imaging modalities. Coronary microvascular dysfunction may be present even if no obstructive lesions are found. Most importantly, non-obstructive coronary artery disease is associated with a heightened risk of future adverse cardiovascular events and should not be ignored. The distinct plaque signature in women should be recognized, and optimal preventive strategies should be performed for both sexes.

Indexed as

AtherosclerosisCoronary Artery DiseasePlaque, AtheroscleroticFemaleHumansMaleRisk FactorsSex FactorsAtherosclerosisCoronary diseasePlaqueSex differences

Identifiers

PMID34081222
PMCPMC9175537
OpenAlexW3165797369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.