Evidence map›Paper›PMID 34081059›Full record

ArticleMedicine and science in sports and exercise2021

Objectively Measured Physical Activity and Body Fatness: Associations with Total Body Fat, Visceral Fat, and Liver Fat.

Esther Winters-VAN Eekelen, Jeroen H P M VAN DER Velde, Sebastiaan C Boone, Kate Westgate, Søren Brage, Hildo J Lamb, Frits R Rosendaal, Renée DE Mutsert

Open access · greenAbstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 25 citations in OpenAlex.

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  16. Habitual Physical Activity and Dietary Profiles in Older Japanese Males with Normal-Weight Obesity.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Esther Winters-VAN EekelenDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, THE NETHERLANDS.
Jeroen H P M VAN DER Velde
Sebastiaan C BooneDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, THE NETHERLANDS.
Kate WestgateMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UNITED KINGDOM.
Søren BrageMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UNITED KINGDOM.
Hildo J LambDepartment of Radiology, Leiden University Medical Center, Leiden, THE NETHERLANDS.
Frits R RosendaalDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, THE NETHERLANDS.
Renée DE MutsertDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, THE NETHERLANDS.
Leiden University Medical Center · NLMRC Epidemiology Unit · GB

Funding

Medical Research Council MC_UU_00006/4Medical Research Council MC_UU_12015/3
6 · The paper itself

Abstract

purposeIt remains unclear to what extent habitual physical activity and sedentary time (ST) are associated with visceral fat and liver fat. We studied the substitution of ST with time spent physically active and total body fat (TBF), visceral adipose tissue (VAT), and hepatic triglyceride content (HTGC) in middle-age men and women.

designIn this cross-sectional analysis of the Netherlands Epidemiology of Obesity study, physical activity was assessed in 228 participants using a combined accelerometer and heart rate monitor. TBF was assessed by the Tanita bioelectrical impedance, VAT by magnetic resonance imaging, and HTGC by proton-MR spectroscopy. Behavioral intensity distribution was categorized as ST, time spent in light physical activity (LPA), and moderate to vigorous physical activity (MVPA). To estimate the effect of replacing 30 min·d-1 of ST with 30 min·d-1 LPA or MVPA, we performed isotemporal substitution analyses, adjusted for sex, age, ethnicity, education, the Dutch Healthy Diet index, and smoking.

resultsIncluded participants (41% men) had a mean ± SD age of 56 ± 6 yr and spent 88 ± 56 min in MVPA and 9.0 ± 2.1 h of ST. Replacing 30 min·d-1 of ST with 30 min of MVPA was associated with 1.3% less TBF (95% confidence interval = -2.0 to -0.7), 7.8 cm2 less VAT (-11.6 to -4.0), and 0.89 times HTGC (0.82-0.97). Replacement with LPA was not associated with TBF (-0.03%; -0.5 to 0.4), VAT (-1.7 cm2; -4.4 to 0.9), or HTGC (0.98 times; 0.92-1.04).

conclusionsReallocation of time spent sedentary with time spent in MVPA, but not LPA, was associated with less TBF, visceral fat, and liver fat. These findings contribute to the development of more specified guidelines on ST and physical activity.

Indexed as

AdiposityExerciseAccelerometryAdipose TissueAgedCross-Sectional StudiesElectric ImpedanceElectrocardiography, AmbulatoryFemaleHumansIntra-Abdominal FatLiverMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedTriglycerides

Identifiers

PMID34081059
PMCPMC7611840
OpenAlexW3164081751

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.