Evidence map›Paper›PMID 34080661›Full record

ArticleOncology reports2021

Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelial‑mesenchymal transition and inhibition of MMP‑2.

Yi-Ching Chuang, Ming-Chang Hsieh, Chia-Chieh Lin, Yu-Sheng Lo, Hsin-Yu Ho, Ming-Ju Hsieh, Jen-Tsun Lin

Open access · hybridAbstract read
In one paragraph

Article in Oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Ethnopharmacology ofFrontiers in pharmacology · 2025
    Review
  4. Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yi-Ching Chuang *Oral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan, R.O.C.
Ming-Chang Hsieh *School of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung 40201, Taiwan, R.O.C.
Chia-Chieh LinOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan, R.O.C.
Yu-Sheng LoOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan, R.O.C.
Hsin-Yu HoOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan, R.O.C.
Ming-Ju HsiehOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan, R.O.C.
Jen-Tsun LinPost Baccalaureate Medicine, National Chung Hsing University, Taichung 40201, Taiwan, R.O.C.
Changhua Christian Hospital · TWNational Chung Hsing University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is a tumor located in the nasopharynx with highly invasive and metastatic properties. Metastasis is a primary cause of mortality in patients with NPC. The terpenoid polyphenol pinosylvin is a known functional compound of the

Indexed as

Antigens, CDCadherinsCell Line, TumorCell MovementCell ProliferationDown-RegulationEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansMatrix Metalloproteinase 2Matrix Metalloproteinase 9Nasopharyngeal CarcinomaNasopharyngeal NeoplasmsPhytoalexinsProteomicsStilbenesAntigens, CDCadherinsCDH2 protein, humanMatrix Metalloproteinase 2Matrix Metalloproteinase 9MMP2 protein, humanMMP9 protein, humanPhytoalexinspinosylvinStilbenesVimentinVIM protein, humanepithelial‑mesenchymal transitionMAPKmatrix metalloproteinasenasopharyngeal cancerpinosylvin

Identifiers

PMID34080661
PMCPMC8165580
OpenAlexW3164812586

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.