Evidence map›Paper›PMID 34080660›Full record

ArticleOncology reports2021

Mechanism of hydrogen on cervical cancer suppression revealed by high‑throughput RNA sequencing.

Jing Chu, Jinghai Gao, Jing Wang, Lingling Li, Guoqiang Chen, Jianhong Dang, Zhifeng Wang, Zhijun Jin, Xiaojun Liu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. A Systematic Review of Molecular Hydrogen Therapy in Cancer Management.Asian Pacific journal of cancer prevention : APJCP · 2023
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jing Chu *Department of Obstetrics and Gynaecology, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Jinghai Gao *Department of Obstetrics and Gynaecology, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Jing WangDepartment of Obstetrics and Gynaecology, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Lingling LiDepartment of Obstetrics and Gynaecology, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Guoqiang ChenDepartment of Obstetrics and Gynaecology, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Jianhong DangDepartment of Obstetrics and Gynaecology, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Zhifeng WangDepartment of Obstetrics and Gynaecology, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Zhijun JinDepartment of Obstetrics and Gynaecology, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Xiaojun LiuDepartment of Obstetrics and Gynaecology, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Shanghai Changzheng Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer is considered one of the diseases with the highest mortality among women and with limited treatment options. Hydrogen (H

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorCell ProliferationCell SurvivalFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHeLa CellsHigh-Throughput Nucleotide SequencingHumansHydrogenHypoxia-Inducible Factor 1, alpha SubunitMiceReactive Oxygen SpeciesSequence Analysis, RNAAntineoplastic AgentsHIF1A protein, humanHydrogenHypoxia-Inducible Factor 1, alpha SubunitReactive Oxygen SpeciesRELA protein, humanTranscription Factor RelAcervical cancerhydrogen gashypoxia‑inducible factor 1αnuclear factor‑κB p65RNA sequencing

Identifiers

PMID34080660
PMCPMC8165587
OpenAlexW3198251984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.