Evidence map›Paper›PMID 34080657›Full record

ArticleMolecular medicine reports2021

Ophiopogonin B induces reactive oxygen species‑dependent apoptosis through the Hippo pathway in nasopharyngeal carcinoma.

Wenhui Dong, Qing Dong, Hairui Ding

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Wenhui DongDepartment of Otorhinolaryngology, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China.
Qing DongDepartment of Operating Room, Weifang Yidu Central Hospital, Weifang, Shandong 262500, P.R. China.
Hairui DingDepartment of Emergency, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China.
Weifang People's Hospital · CNYidu Central Hospital of Weifang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is a common malignant tumor in South China and is characterized by a high death rate. Ophiopogonin B (OP‑B) is a bioactive component of Radix

Indexed as

AnimalsApoptosisCell Line, TumorCell ProliferationCell SurvivalHippo Signaling PathwayHumansMembrane Potential, MitochondrialNasopharyngeal CarcinomaNasopharyngeal NeoplasmsProtein Serine-Threonine KinasesReactive Oxygen SpeciesSaponinsSignal TransductionSpirostansLATS1 protein, humanophiopogonin BProtein Serine-Threonine KinasesReactive Oxygen SpeciesSaponinsSpirostansHippo pathwaynasopharyngeal carcinomaophiopogonin B

Identifiers

PMID34080657
PMCPMC8170196
OpenAlexW3165751030

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.