ArticleCerebral cortex (New York, N.Y. : 1991)2021
Cross-Diagnosis Structural Correlates of Autistic-Like Social Communication Differences.
Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Artificial intelligence in ADHD: a global perspective on research hotspots, trends and clinical applications.Frontiers in human neuroscience · 2025Pooled it
- Connectome-based symptom mapping and in silico related gene expression in children with autism and/or attention-deficit/hyperactivity disorder.Molecular psychiatry · 2026Article
- A naturalistic, non-invasive method for capturing biometric data during autism evaluations.Frontiers in psychiatry · 2026Article
- Transdiagnostic Behavioral Phenotypes and Comorbid Gastrointestinal Symptoms in Neurodevelopmental Disorders: An Exploratory Study.Autism research : official journal of the International Society for Autism Research · 2026Article
- EEG neurosubtyping of infants predicts language trajectories.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- The Development of Lateralized Brain Oscillations in Infants: Lessons From Autism.Developmental psychobiology · 2025Article
- Characterizing replicability in the clustering structure of brain morphology in autism, attention-deficit/hyperactivity disorder, and obsessive compulsive disorder.Translational psychiatry · 2025Article
- Using deep learning to predict internalizing problems from brain structure in youth.Translational psychiatry · 2025Article
- Using deep learning to predict internalizing problems from brain structure in youth.bioRxiv : the preprint server for biology · 2025Article
- Understanding social behaviours across neurodiverse young people: roles of social cognition and self-regulation.BJPsych open · 2025Article
- Connectome-based symptom mapping andmedRxiv : the preprint server for health sciences · 2024Article
- Dataset factors associated with age-related changes in brain structure and function in neurodevelopmental conditions.Human brain mapping · 2024Article
- Behaviour-correlated profiles of cerebellar-cerebral functional connectivity observed in independent neurodevelopmental disorder cohorts.Translational psychiatry · 2024Article
- Predictors of health-related quality of life for children with neurodevelopmental conditions.Scientific reports · 2024Article
- Identifying Replicable Subgroups in Neurodevelopmental Conditions Using Resting-State Functional Magnetic Resonance Imaging Data.JAMA network open · 2023Article
- Candidate diagnostic biomarkers for neurodevelopmental disorders in children and adolescents: a systematic review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023Article
- Investigating heterogeneity across autism, ADHD, and typical development using measures of cortical thickness, surface area, cortical/subcortical volume, and structural covariance.Frontiers in child and adolescent psychiatry · 2023Article
- Editorial: Precision medicine approaches for heterogeneous conditions such as autism spectrum disorders (The need for a biomarker exploration phase in clinical trials - Phase 2m).Frontiers in psychiatry · 2022Article
- Shared and Distinct Patterns of Functional Connectivity to Emotional Faces in Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder Children.Frontiers in psychology · 2022Article
Corrections and comments
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Authors and funding
17 authors at 8 institutions in 2 countries.
Funding
Abstract
Social communication differences are seen in autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and obsessive-compulsive disorder (OCD), but the brain mechanisms contributing to these differences remain largely unknown. To address this gap, we used a data-driven and diagnosis-agnostic approach to discover brain correlates of social communication differences in ASD, ADHD, and OCD, and subgroups of individuals who share similar patterns of brain-behavior associations. A machine learning pipeline (regression clustering) was used to discover the pattern of association between structural brain measures (volume, surface area, and cortical thickness) and social communication abilities. Participants (n = 416) included children with a diagnosis of ASD (n = 192, age = 12.0[5.6], 19% female), ADHD (n = 109, age = 11.1[4.1], 18% female), or OCD (n = 50, age = 12.3[4.2], 42% female), and typically developing controls (n = 65, age = 11.6[7.1], 48% female). The analyses revealed (1) associations with social communication abilities in distributed cortical and subcortical networks implicated in social behaviors, language, attention, memory, and executive functions, and (2) three data-driven, diagnosis-agnostic subgroups based on the patterns of association in the above networks. Our results suggest that different brain networks may contribute to social communication differences in subgroups that are not diagnosis-specific.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.