Evidence map›Paper›PMID 34080514›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2021

Synthesis and biological evaluation of thiazolidinedione derivatives with high ligand efficiency to

Thamires Quadros Froes, Bianca Trindade Chaves, Marina Sena Mendes, Rafael Matos Ximenes, Ivanildo Mangueira da Silva, Priscila Brandão Gomes da Silva, Julianna Ferreira Cavalcanti de Albuquerque, Marcelo Santos Castilho

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. 1Current topics in medicinal chemistry · 2024
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thamires Quadros FroesPrograma de Pós-graduação em biotecnologia da, Universidade Estadual de Feira de Santana, Feira de Santana, Brazil.
Bianca Trindade ChavesFaculdade de Farmácia da, Universidade Federal da Bahia, Salvador, Brazil.
Marina Sena MendesFaculdade de Farmácia da, Universidade Federal da Bahia, Salvador, Brazil.
Rafael Matos XimenesDepartamento de Antibióticos da, Universidade Federal de Pernambuco. Av. Prof. Moraes Rego, Recife-Pe, Brazil.
Ivanildo Mangueira da SilvaDepartamento de Antibióticos da, Universidade Federal de Pernambuco. Av. Prof. Moraes Rego, Recife-Pe, Brazil.
Priscila Brandão Gomes da SilvaDepartamento de Antibióticos da, Universidade Federal de Pernambuco. Av. Prof. Moraes Rego, Recife-Pe, Brazil.
Julianna Ferreira Cavalcanti de AlbuquerqueDepartamento de Antibióticos da, Universidade Federal de Pernambuco. Av. Prof. Moraes Rego, Recife-Pe, Brazil.
Marcelo Santos CastilhoPrograma de Pós-graduação em biotecnologia da, Universidade Estadual de Feira de Santana, Feira de Santana, Brazil.ORCID https://orcid.org/0000-0002-9563-5679

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The thiazolidinone ring is found in compounds that have widespan biology activity and there is mechanism-based evidence that compounds bearing this moiety inhibit

Indexed as

Anti-Bacterial AgentsHumansLigandsPseudomonas aeruginosaThiazolidinedionesAnti-Bacterial AgentsLigandsThiazolidinedionesantimicrobial resistanceP. aeruginosapyocyanin biosynthesis inhibitionThiazolidinone

Identifiers

PMID34080514
PMCPMC8186431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.