Evidence map›Paper›PMID 34080344›Full record

ArticleJournal of cardiovascular imaging2021

Epidemiology of Venous Thromboembolism and Treatment Pattern of Oral Anticoagulation in Korea, 2009-2016: a Nationwide Study Based on the National Health Insurance Service Database.

Hyung Yoon Kim, Sung A Chang, Kye Hun Kim, Jae Young Kim, Woo Keun Seo, Hyungseop Kim, Jeong Sook Seo, Sung Hee Shin, Sang Jae Rhee, Sun Hwa Lee and 2 more

Abstract read
In one paragraph

Article in Journal of cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hyung Yoon KimDepartment of Cardiovascular Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0002-0692-5640
Sung A ChangDepartment of Internal Medicine, Cardiovascular Imaging Center, Heart, Vascular & Stroke Institute, Sungkyunkwan University School of Medicine, Seoul, Korea. elisabet.chang@gmail.com.ORCID https://orcid.org/0000-0001-5124-605X
Kye Hun KimDepartment of Cardiovascular Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea. christiankyehun@hanmail.net.ORCID https://orcid.org/0000-0002-6885-1501
Jae Young KimDepartment of Neurology and Stroke Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9628-421X
Woo Keun SeoDepartment of Neurology and Stroke Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4004-8434
Hyungseop KimDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea.ORCID https://orcid.org/0000-0001-7056-4221
Jeong Sook SeoDivision of Cardiology, Department of Internal Medicine, Busan Paik Hospital, Inje University, Busan, Korea.ORCID https://orcid.org/0000-0001-6724-4227
Sung Hee ShinDivision of Cardiology, Department of Internal Medicine, Inha University Hospital, Incheon, Korea.ORCID https://orcid.org/0000-0002-8306-9622
Sang Jae RheeDepartment of Cardiovascular Medicine, Wonkwang University Hospital, Iksan, Korea.ORCID https://orcid.org/0000-0001-9738-0481
Sun Hwa LeeDepartment of Cardiology in Internal Medicine, Jeonbuk National University Medical School and Hospital, Jeonju, Korea.ORCID https://orcid.org/0000-0001-9752-9717
Jung Sun ChoDepartment of Cardiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-0308-0021
Venous Thromboembolism Research Group of Korean Society of Echocardiography

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe annual incidence of venous thromboembolism (VTE) is increasing, and the treatment pattern of oral anticoagulants (OACs) has changed with introduction of new oral anticoagulants (NOACs). The aims of this study were to assess the annual incidence of VTE in a Korean population and the change of treatment pattern with availability of NOACs using a population-based database.

methodsUsing the Korean National Health Insurance Services database, we identified patients diagnosed with VTE between 2009 and 2016. The annual prevalence of VTE and clinical characteristics and treatment pattern were investigated. The annual incidence of VTE was calculated using direct and indirect methods using the estimated Korean population in 2009 as the reference.

resultsThe annual incidence of VTE in Korean has increased yearly from 23.9 per 100,000 in 2009 to 42.2 in 2016. The overall rate of OAC prescription for VTE treatment increased from 55.9% to 68% in the same time period. The rate of initiation of NOAC treatment greatly increased, particularly from 2013 onwards, with a 20-fold increase from 2009 to 2016 (2.1% vs. 54.3%).

conclusionsThe annual incidence of VTE in Korea increased by almost two-fold from 2009 to 2016. The rate of initiation of NOAC treatment has increased substantially since 2013, and these agents have surpassed VKAs as the anticoagulant of choice for VTE. This temporal pattern of OAC prescription is consistent with the current clinical guidelines, which indicate NOACs over the warfarin in patients with VTE.

Indexed as

Annual incidenceNOACsOral anticoagulantsTemporal trendVenous thromboembolism

Identifiers

PMID34080344
PMCPMC8318819

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.