ArticleJournal of sleep research2021
Sleep difficulties, incident dementia and all-cause mortality among older adults across 8 years: Findings from the National Health and Aging Trends Study.
Article in Journal of sleep research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Pooled it
- Pain and mild cognitive impairment among adults aged 50 years and above residing in low- and middle-income countries.Aging clinical and experimental research · 2023Pooled it
- High dose melatonin increases sleep duration during nighttime and daytime sleep episodes in older adults.Journal of pineal research · 2022Trial
- Non-restorative Sleep and Functional Limitation in United States Adults Aged 25-74 Years: A Propensity Score-matched Analysis.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2026Article
- Association of obstructive sleep apnoea with exercise capacity and mortality in a population-based study: results of SHIP-TREND.ERJ open research · 2026Article
- Obstructive sleep apnea and functional hearing loss over 8 years: results from the National Health and Aging Trends Study.American journal of epidemiology · 2026Article
- Subjective-Device-Estimated Sleep Discrepancies in Late-Life Depression: Agreement and Associated Factors.Alpha psychiatry · 2026Article
- Association of Motoric Cognitive Risk Syndrome and Its Components with Health Indicators in Community-dwelling Older Adults: A Cross-sectional Study.Progress in rehabilitation medicine · 2026Article
- Losses to Follow-Up in a Nationally Representative Study of Community-Living Older Americans: Two Approaches to Censoring and Implications for Mortality Outcomes.Journal of the American Geriatrics Society · 2026Article
- U shaped association between sleep duration and long term cognitive decline trajectories in a national cohort.Scientific reports · 2025Article
- Long-term quality of life of testicular cancer survivors differs according to applied adjuvant treatment and tumour type.Journal of cancer survivorship : research and practice · 2025Article
- Incomplete Ascertainment of Mortality in a Nationally Representative Longitudinal Study of Community-Living Older Americans.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Longitudinal associations between symptom burden and fall risks in older adults with a cancer history: Findings from the 2011-2015 National Health and Aging Trends Study.Journal of geriatric oncology · 2025Article
- Race and Incident Dementia Among Older Black and Older White Men.Journal of aging and health · 2025Article
- Effects of chronic diseases on health related quality of life is mediated by sleep difficulty in middle aged and older adults.Scientific reports · 2025Article
- Developing a tool to assess mattress satisfaction: the Boston Mattress Satisfaction Questionnaire.Frontiers in sleep · 2025Article
- Association between sleep problems and functional disability in community-dwelling older adults.BMC geriatrics · 2024Article
- Mid-life sleep is associated with cognitive performance later in life in aging American Indians: data from the Strong Heart Study.Frontiers in aging neuroscience · 2024Article
- Relationship between night shift and sleep problems, risk of metabolic abnormalities of nurses: a 2 years follow-up retrospective analysis in the National Nurse Health Study (NNHS).International archives of occupational and environmental health · 2023Article
- Interactive association between insomnia symptoms and sleep duration for the risk of dementia-a prospective study in the Swedish National March Cohort.Age and ageing · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Sleep difficulties have been implicated in the development and progression of dementia and in all-cause mortality. This study examines the relationship between sleep difficulties, incident dementia and all-cause mortality over 8 years of follow-up among a nationally representative sample of older (≥65 years) adults in the United States. We used data collected from the National Health and Aging Trends Study (NHATS) from 2011 to 2018, a prospective cohort study of Medicare beneficiaries. At baseline, the NHATS sample comprised 6,376 older adults who were representative of 32 million older adults. Respondents reported routine difficulty initiating sleep or difficulty falling back asleep "most nights" or "every night" in each study year. In each year, dementia was determined by either self-reported diagnosis or performance on immediate and delayed recall word and clock drawing tests, whereas all-cause mortality was determined by proxy. We conducted Cox proportional hazards modelling, adjusting for age, sex, marital status and chronic conditions. In models predicting all-cause mortality, we also controlled for dementia. Among respondents at baseline, 19% were 65-75 years of age, 71% identified as non-Hispanic white and 59% were female. Difficulty initiating sleep (hazard ratio [HR], 1.49; 95% confidence interval [CI],1.25-1.77), difficulty falling back asleep (HR, = 1.39; 95% CI,1.14-1.70) and concurrent sleep difficulties (HR, 1.58; 95% CI, 1.25-1.99) were associated with greater risk of dementia. Difficulty initiating sleep (HR, 1.44; 95% CI,1.20-1.72), difficulty falling back asleep (HR, 1.56; 95% CI,1.29-1.89), and concurrent sleep difficulties (HR, 1.80; 95% CI, 1.44-2.24) were associated with greater risk of all-cause mortality. Our findings demonstrate that reported difficulties are prospectively associated with an increased risk of dementia and all-cause mortality among older people.
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Registered trials
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