Evidence map›Paper›PMID 34080153›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Update of Mitochondrial Network Analysis by Imaging: Proof of Technique in Schizophrenia.

Yekaterina Yatchenko, Dorit Ben-Shachar

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Mitochondria-targeted delivery strategies for age-related diseases.International journal of pharmaceutics: X · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yekaterina YatchenkoLaboratory of Psychobiology, Department of Neuroscience, B. Rappaport Faculty of Medicine, Technion IIT, Haifa, Israel.
Dorit Ben-ShacharLaboratory of Psychobiology, Department of Neuroscience, B. Rappaport Faculty of Medicine, Technion IIT, Haifa, Israel. shachar@technion.ac.il.
Technion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria, similar to living cells and organelles, have a negative membrane potential, which ranges between (-108) and (150) mV as compared to (-70) and (-90) mV of the plasma membrane. Therefore, permeable lipophilic cations tend to accumulate in the mitochondria. Those cations which exhibit fluorescence activity after accumulation into energized systems are widely used to decipher changes in membrane potential by imaging techniques. Here we describe the use of two different dyes for labeling mitochondrial membrane potential (Δψ

Indexed as

Membrane Potential, MitochondrialBenzimidazolesCarbocyaninesCell Culture TechniquesFibroblastsFluorescent DyesHumansImage Processing, Computer-AssistedMicroscopy, ConfocalMitochondriaProof of Concept StudySchizophreniaXanthenes5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanineBenzimidazolesCarbocyaninesFluorescent Dyesmitotracker orangeXanthenesJC-1Mitochondrial distributionMitochondrial imagingMitochondrial membrane potentialMitochondrial network connectivityMitoTracker OrangeSchizophrenia

Identifiers

PMID34080153
OpenAlexW3164241571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.