Evidence map›Paper›PMID 34080084›Full record

ArticleJournal of clinical immunology2021

A Case of VEXAS Syndrome Complicated by Hemophagocytic Lymphohistiocytosis.

Alice Grey, Pak Leng Cheong, Frederick J Lee, Edward Abadir, James Favaloro, Shihong Yang, Stephen Adelstein

Abstract readCase ReportsLetter
PubMed Publisher
In one paragraph

Article in Journal of clinical immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Clinical features in VEXAS syndrome: a systematic review.Rheumatology (Oxford, England) · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. VEXAS Syndrome-Review.Global medical genetics · 2023
    Review
  12. Article
  13. Review
  14. [VEXAS syndrome].Zeitschrift fur Rheumatologie · 2022
    Review
  15. Disorders of ubiquitylation: unchained inflammation.Nature reviews. Rheumatology · 2022
    Review
  16. Thrombosis in VEXAS syndrome.Journal of thrombosis and thrombolysis · 2022
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alice GreyDepartment of Clinical Immunology and Allergy, Royal Prince Alfred Hospital, Sydney, Australia. alice.grey@health.nsw.gov.au.ORCID http://orcid.org/0000-0002-7000-3384
Pak Leng CheongDepartment of Medical Genomics, Royal Prince Alfred Hospital, Sydney, Australia.ORCID https://orcid.org/0000-0002-0095-4459
Frederick J LeeDepartment of Clinical Immunology and Allergy, Royal Prince Alfred Hospital, Sydney, Australia.
Edward AbadirDepartment of Haematology, Royal Prince Alfred Hospital, Sydney, Australia.
James FavaloroDepartment of Haematology, Royal Prince Alfred Hospital, Sydney, Australia.
Shihong YangDepartment of Haematology, Royal Prince Alfred Hospital, Sydney, Australia.
Stephen AdelsteinDepartment of Clinical Immunology and Allergy, Royal Prince Alfred Hospital, Sydney, Australia.
Royal Prince Alfred Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Diseases, X-LinkedHereditary Autoinflammatory DiseasesLymphohistiocytosis, HemophagocyticAgedCytokinesHumansMaleSyndromeUbiquitin-Activating EnzymesCytokinesUBA1 protein, humanUbiquitin-Activating Enzymes

Identifiers

PMID34080084
OpenAlexW3165496050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.