Evidence map›Paper›PMID 34079932›Full record

ArticleFrontiers in artificial intelligence2021

A Transfer Learning-Based Active Learning Framework for Brain Tumor Classification.

Ruqian Hao, Khashayar Namdar, Lin Liu, Farzad Khalvati

Abstract read
In one paragraph

Article in Frontiers in artificial intelligence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

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0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  12. Deep learning in precision medicine and focus on glioma.Bioengineering & translational medicine · 2023
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Ruqian HaoSchool of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu, China.
Khashayar NamdarDepartment of Medical Imaging, University of Toronto, Toronto, ON, Canada.
Lin LiuSchool of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu, China.
Farzad KhalvatiInstitute of Medical Science, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain tumor is one of the leading causes of cancer-related death globally among children and adults. Precise classification of brain tumor grade (low-grade and high-grade glioma) at an early stage plays a key role in successful prognosis and treatment planning. With recent advances in deep learning, artificial intelligence-enabled brain tumor grading systems can assist radiologists in the interpretation of medical images within seconds. The performance of deep learning techniques is, however, highly depended on the size of the annotated dataset. It is extremely challenging to label a large quantity of medical images, given the complexity and volume of medical data. In this work, we propose a novel transfer learning-based active learning framework to reduce the annotation cost while maintaining stability and robustness of the model performance for brain tumor classification. In this retrospective research, we employed a 2D slice-based approach to train and fine-tune our model on the magnetic resonance imaging (MRI) training dataset of 203 patients and a validation dataset of 66 patients which was used as the baseline. With our proposed method, the model achieved area under receiver operating characteristic (ROC) curve (AUC) of 82.89% on a separate test dataset of 66 patients, which was 2.92% higher than the baseline AUC while saving at least 40% of labeling cost. In order to further examine the robustness of our method, we created a balanced dataset, which underwent the same procedure. The model achieved AUC of 82% compared with AUC of 78.48% for the baseline, which reassures the robustness and stability of our proposed transfer learning augmented with active learning framework while significantly reducing the size of training data.

Indexed as

active learningbrain tumorclassificationMRItransfer learning

Identifiers

PMID34079932
PMCPMC8165261

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.