Evidence map›Paper›PMID 34079930›Full record

ArticleFrontiers in artificial intelligence2021

Virtual Cohorts and Synthetic Data in Dementia: An Illustration of Their Potential to Advance Research.

Graciela Muniz-Terrera, Ofer Mendelevitch, Rodrigo Barnes, Michael D Lesh

Abstract read
In one paragraph

Article in Frontiers in artificial intelligence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Graciela Muniz-TerreraEdinburgh Dementia Prevention Group, University of Edinburgh, Edinburgh, United Kingdom.
Ofer MendelevitchSyntegra, San Carlos, CA, United States.
Rodrigo BarnesAridhia Informatics, Glasgow, United Kingdom.
Michael D LeshSyntegra, San Carlos, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When attempting to answer questions of interest, scientists often encounter hurdles that may stem from limited access to existing adequate datasets as a consequence of poor data sharing practices, constraining administrative practices. Further, when attempting to integrate data, differences in existing datasets also impose challenges that limit opportunities for data integration. As a result, the pace of scientific advancements is suboptimal. Synthetic data and virtual cohorts generated using innovative computational techniques represent an opportunity to overcome some of these limitations and consequently, to advance scientific developments. In this paper, we demonstrate the use of virtual cohorts techniques to generate a synthetic dataset that mirrors a deeply phenotyped sample of preclinical dementia research participants.

Indexed as

AI/MLcohortsdementiasynthetic datavirtual cohort

Identifiers

PMID34079930
PMCPMC8165312

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.