Evidence map›Paper›PMID 34079729›Full record

ArticleQuantitative imaging in medicine and surgery2021

Clinical efficacy of laser therapy in the prevention of retinal detachment in patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis.

Lian-Yong Xie, Xiao-Na Li, Chao Chen, Wen-Jun Kong, Tai-Yi Jiang, Kui-Fang Du, Hong-Wei Dong, Chun-Gang Guo, Wen-Bin Wei

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Lian-Yong XieDepartment of Ophthalmology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Xiao-Na LiDepartment of Ophthalmology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Chao ChenDepartment of Ophthalmology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Wen-Jun KongDepartment of Ophthalmology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Tai-Yi JiangDepartment of Infectious Diseases, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Kui-Fang DuDepartment of Ophthalmology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Hong-Wei DongDepartment of Ophthalmology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Chun-Gang GuoDepartment of Ophthalmology, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Wen-Bin WeiBeijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CNBeijing YouAn Hospital · CNMinistry of Industry and Information Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the present study was to evaluate the clinical efficacy of laser therapy in the prevention of retinal detachment in patients with acquired immunodeficiency syndrome (AIDS) and cytomegalovirus retinitis (CMVR).

methodsA total of 96 eyes from 80 patients with AIDS and CMVR who received anticytomegalovirus (anti-CMV) treatment in the ophthalmology and infection centers of Beijing YouAn Hospital, between June 2016 and August 2018 were retrospectively investigated. The patients were randomly divided into a nonlaser group (50 eyes from 43 patients), who were treated with anti-CMV therapy, and a laser group (46 eyes from 37 patients), who were treated with a fundus laser method to close the retinopathy area after commencing the maintenance stage of anti-CMV treatment. Both groups were followed up for 24 months. The safety of laser therapy was observed, and the efficacy of the therapy was determined by evaluating the incidence of retinal detachment.

resultsThe percentage of retinal detachment in the nonlaser group was 24% compared with 6.5% in the laser group (P=0.018). There was no significant difference between the two groups in the number of CD4

conclusionsThe use of laser therapy in the main maintenance period of anti-CMV treatment can effectively reduce the incidence of retinal detachment in patients with AIDS and CMVR, and the therapy is safe and reliable.

Indexed as

Cytomegalovirus retinitis (CMVR)laser therapyretinal detachmenttherapeutic efficacy

Identifiers

PMID34079729
PMCPMC8107343
OpenAlexW3155576761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.