Evidence map›Paper›PMID 34079709›Full record

ArticleQuantitative imaging in medicine and surgery2021

A novel wireless optical technique for quantitative evaluation of cerebral perfusion pressure in a fluid percussion animal model of traumatic brain injury.

Yao-Kuang Huang, Chin-Kuo Lin, Che-Chuan Wang, Jinn-Rung Kuo, Chien-Fu Lai, Chien-Wei Chen, Bor-Shyh Lin

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yao-Kuang HuangDivision of Cardiovascular Surgery and Radiology, Chiayi Chang Gung Memorial Hospital, Putz, Chiayi.
Chin-Kuo LinCollege of Medicine, Chang Gung University, Taoyuan.
Che-Chuan WangDivision of Neurosurgery, Department of Surgery, Chi Mei Medical Center, Tainan.
Jinn-Rung KuoDivision of Neurosurgery, Department of Surgery, Chi Mei Medical Center, Tainan.
Chien-Fu LaiInstitute of Imaging and Biomedical Photonics, National Yang Ming Chiao Tung University, Tainan.
Chien-Wei ChenDivision of Cardiovascular Surgery and Radiology, Chiayi Chang Gung Memorial Hospital, Putz, Chiayi.
Bor-Shyh LinInstitute of Imaging and Biomedical Photonics, National Yang Ming Chiao Tung University, Tainan.
Chiayi Chang Gung Memorial Hospital · TWChi Mei Medical Center · TWNational Yang Ming Chiao Tung University · TWChang Gung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral perfusion pressure (CPP) calculated by mean arterial pressure (MAP) minus intracranial pressure (ICP) is related to blood flow into the brain and reflects cerebral ischemia and oxygenation indirectly. Near-infrared spectroscopy (NIRS) can assess cerebral ischemia and hypoxia non-invasively and has been widely used in neuroscience. However, the correlation between CPP and NIRS, and its potential application in traumatic brain injury, has seldom been investigated.

methodsWe used a novel wireless NIRS system and commercial ICP and MAP devices to assess the trauma to rat brains using different impact intensity. The relationship between CPP and NIRS parameters with increasing impact strength were investigated.

resultsThe results showed that changes in CPP (∆CPP), oxy-hemoglobin {∆[HbO

conclusionsThe NIRS system can assess cerebral ischemia and oxygenation non-invasively and changes of HbO

Indexed as

cerebral perfusion pressure (CPP)deoxy-hemoglobinNear-infrared spectroscopy (NIRS)oxy-hemoglobin (HbO2)total-hemoglobin (HbT)traumatic brain injury (TBI)

Identifiers

PMID34079709
PMCPMC8107305
OpenAlexW3156391916

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.