Evidence map›Paper›PMID 34079641›Full record

ArticleAmerican journal of nuclear medicine and molecular imaging2021

Evaluation of quantitative modeling methods in whole-body, dynamic [

Joseph Ryan Petrulli, Mingqiang Zheng, Yiyun Huang, Nabeel B Nabulsi, Sarah B Goldberg, Joseph N Contessa, Evan D Morris

Open access · greenAbstract read
In one paragraph

Article in American journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Joseph Ryan PetrulliDepartment of Biomedical Engineering, Yale University New Haven, CT, United States.
Mingqiang ZhengDepartment of Radiology and Biomedical Imaging, Yale University New Haven, CT, United States.
Yiyun HuangDepartment of Radiology and Biomedical Imaging, Yale University New Haven, CT, United States.
Nabeel B NabulsiDepartment of Radiology and Biomedical Imaging, Yale University New Haven, CT, United States.
Sarah B GoldbergDepartment of Therapeutic Radiology, Yale University New Haven, CT, United States.
Joseph N ContessaDepartment of Therapeutic Radiology, Yale University New Haven, CT, United States.
Evan D MorrisDepartment of Biomedical Engineering, Yale University New Haven, CT, United States.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
Yale University Clinical and Translational Science Award ProgramKL2RR024138 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$4.8M
Validation of Quantitative 11C-Erlotinib PET for Imaging EGFR-Mutant Lung CancerR01CA195493 · NCI · YALE UNIVERSITY · PI CONTESSA, JOSEPH N, MORRIS, EVAN D · 2015 to 2017
$768k
NCATS NIH HHS UL1 TR001863NCI NIH HHS R01 CA195493NCRR NIH HHS KL2 RR024138NCRR NIH HHS UL1 RR024139
6 · The paper itself

Abstract

background[

resultsStandard uptake values (a semi-quantitative endpoint) were well correlated with both binding potential and volume of distribution (fully quantitative endpoints). Normalized tracer uptake was found to stabilize approximately 60 minutes post tracer injection.

Indexed as

ErlotinibNSCLCPETquantitative imagingTKI

Identifiers

PMID34079641
PMCPMC8165727
OpenAlexW3164814731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.