Observational studyFrontiers in endocrinology2021
Predictor Analysis in Radiofrequency Ablation of Benign Thyroid Nodules: A Single Center Experience.
Observational study in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Long-term clinical outcomes of thermal ablation for benign thyroid nodules and unresolved issues: a comprehensive systematic review.La Radiologia medica · 2025Pooled it
- Early volume reduction slope as a novel predictor of long-term outcomes following microwave ablation of benign thyroid nodules: a machine learning-enhanced prediction model.Journal of ultrasound · 2026Article
- Single-session radiofrequency ablation versus microwave ablation of predominantly solid benign thyroid nodules-a comparison after propensity score matching for initial nodule volumes and diameters.European radiology · 2026Article
- Comparing the therapeutic efficacy of radiofrequency vs. Microwave ablation for non-functioning benign thyroid nodules.Journal of endocrinological investigation · 2026Article
- Improving radiofrequency ablation outcomes in large thyroid nodules: superiority of adjustable tip needles.Frontiers in endocrinology · 2026Observational
- Comparison of two ablation methods in benign thyroid nodules: Radiofrequency ablation and non-cooled microwave ablation.Journal of clinical imaging science · 2026Article
- Predictors of Suboptimal Response After Radiofrequency Ablation of Benign Thyroid Nodules.Journal of clinical medicine · 2025Article
- Nano-approaches and Recent Advancements in Strategies to Combat Challenges Associated with Thyroid Cancer Therapies.Recent patents on nanotechnology · 2025Review
- Proficiency in performing radiofrequency ablation procedure for non-functioning benign thyroid nodules: a qualitative rather than quantitative matter.Frontiers in endocrinology · 2024Article
- [Clinical Approach for Thyroid Radiofrequency Ablation].Journal of the Korean Society of Radiology · 2023Review
- Effect of ultrasound parameters of benign thyroid nodules on radiofrequency ablation efficacy.BMC medical imaging · 2023Article
- The influence of nodule size on clinical efficacy of ethanol ablation and microwave ablation on cystic or predominantly cystic thyroid nodules.Endocrine connections · 2022Article
- Radiofrequency Ablation of Indeterminate Thyroid Nodules: The First North American Comparative Analysis.International journal of molecular sciences · 2022Article
- Ultrasound grayscale ratio: a reliable parameter for differentiating between papillary thyroid microcarcinoma and micronodular goiter.BMC endocrine disorders · 2022Article
- Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules.Saudi medical journal · 2021Article
- Successful Ultrasound Guided Sclerotherapy Technique for the Management of a Microcystic Warthin's Tumor.Journal of medical ultrasoundArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To confirm the efficacy of ultrasound (US) guided radiofrequency ablation (RFA) in the treatment of benign thyroid nodules, we evaluated as primary outcome the technical efficacy and clinical success in a single center dataset. The secondary outcome was to find a correlation between nodules' pre-treatment features and volume reduction rate (VRR) ≥75% at 12 months after RFA and during follow-up period. Methods: This retrospective study included 119 consecutive patients (99 females, 20 males, 51.5 ± 14.4 years) with benign thyroid nodules treated in our hospital between October 2014 and December 2018 with a mean follow-up of 26.8 months (range 3-48). Clinical and US features before and after RFA were evaluated by a US examination at 1, 3, 6, 12 months and annually thereafter up to 48 months. Results: The median pre-treatment volume was 22.4 ml; after RFA we observed a statistically significant volume reduction from the first month (11.7 ml) to the last follow-up (p < 0.001 for all follow-up times). The median VRR was 47.1, 55.3, 61.2, 67.6, 72.8, 71.3, and 62.9% at 1, 3, 6, 12, 24, 36, and 48 months of follow-up respectively, showing a progressive significant improvement up to 24 months (VRRs 1 Conclusions: This study confirmed the efficacy of RFA in the treatment of benign thyroid nodules. In particular we show that by selecting macrocystic nodules smaller than 22.4 ml better long-term response can be achieved, which is predicted by an early shrinkage of the nodule.
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