Evidence map›Paper›PMID 34079394›Full record

ReviewHepatic medicine : evidence and research2021

Step by Step: Managing the Complications of Cirrhosis.

Irene C Perez, Fabian J Bolte, William Bigelow, Zachary Dickson, Neeral L Shah

Open access · goldAbstract readReview
In one paragraph

Review in Hepatic medicine : evidence and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Metabolic Dysfunction-Associated Steatohepatitis Diagnosis and Management in Germany: Insights From an Expert Consensus Panel.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  3. Article
  4. Biomolecules & biomedicine · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Irene C PerezDepartment of Internal Medicine, University of Virginia, Charlottesville, VA, USA.
Fabian J BolteDepartment of Internal Medicine, University of Virginia, Charlottesville, VA, USA.
William BigelowDepartment of Internal Medicine, University of Virginia, Charlottesville, VA, USA.
Zachary DicksonDivision of Gastroenterology and Hepatology, University of Virginia, Charlottesville, VA, USA.
Neeral L ShahDivision of Gastroenterology and Hepatology, University of Virginia, Charlottesville, VA, USA.
University of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the Centers for Disease Control and Prevention, chronic liver disease and cirrhosis is the 11th leading cause of death in the United States. Common causes of chronic liver disease include alcohol, viral hepatitis, and non-alcoholic steatohepatitis (NASH). Inflammation is a critical driver in the progression of liver disease to liver fibrosis and ultimately cirrhosis. While the severity of chronic liver disease extends over a continuum, the management is more easily differentiated between compensated and decompensated cirrhosis. In this review, we discuss pathophysiology, clinical features and management of common complications of liver cirrhosis based on literature review and the current clinical practice guidelines of the American Association for the Study of Liver Diseases (AASLD).

Indexed as

chronic liver diseasecirrhosiscompensated cirrhosisdecompensated cirrhosisend-stage liver diseasehepatorenal syndrome

Identifiers

PMID34079394
PMCPMC8164676
OpenAlexW3164959806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.