Evidence map›Paper›PMID 34079389›Full record

ArticleInternational medical case reports journal2021

Optic Neuritis in a Patient with Seropositive Myelin Oligodendrocyte Glycoprotein Antibody During the Post-COVID-19 Period.

Lepša Žorić, Isidora Rajović-Mrkić, Emina Čolak, Dijana Mirić, Bojana Kisić

Open access · goldAbstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Effects of coronavirus disease 2019 in patients with optic neuritis: a single-centre retrospective cohort study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  3. Review of atypical optic neuritis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. A review of neurological side effects of COVID-19 vaccination.European journal of medical research · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. COVID-19 Vaccination and The Eye.American journal of ophthalmology · 2022
    Review
  14. SARS-COV-2 a trigger of myelin oligodendrocyte glycoprotein-associated disorder.Annals of clinical and translational neurology · 2022
    Article
  15. Article
  16. Article
  17. Post COVID-19 neurological complications; a meta-analysis.Annals of medicine and surgery (2012) · 2022
    Review
  18. Article
  19. Post COVID-19 Vaccination-Associated Neurological Complications.Neuropsychiatric disease and treatment · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lepša ŽorićFaculty of Medicine, University of Pristina Settled in Kosovska Mitrovica (UPKM), Kosovska Mitrovica, Serbia.ORCID 0000-0003-1237-6470
Isidora Rajović-MrkićOphthalmology Department, Clinical Center of Kosovska Mitrovica, Kosovska Mitrovica, Serbia.
Emina ČolakInstitute of Medical Biochemistry, Clinical Center of Serbia, Belgrade, Serbia.
Dijana MirićInstitute of Medical Biochemistry, Faculty of Medicine, University of Priština Settled in Kosovska Mitrovica (UPKM), Kosovska Mitrovica, Serbia.
Bojana KisićInstitute of Medical Biochemistry, Faculty of Medicine, University of Priština Settled in Kosovska Mitrovica (UPKM), Kosovska Mitrovica, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reports of neuro-ophthalmological manifestations and complications in patients with coronavirus disease 19 (COVID-19) are still scarce. The aim of this article is to present optic neuritis, as possible post-infectious manifestation of COVID-19. Four weeks after hospitalization for seropositive coronavirus disease 19 (COVID-19), presented as bilateral bronchopneumonia, with radiology and laboratory findings also pointed to high clinical suspicion to COVID-19, a 63-year-old man developed a headache and subacute and profound visual loss on his right eye. The disease presentation was the right eye papillitis. Inflammatory parameters were normal at the time of hospitalization, and IgM and IgG for SARS-CoV-2 were still positive. After corticosteroid pulse therapy, his vision improved significantly and on follow-up visits returned to normal. All laboratory and radiology findings were unremarkable, except for antibodies against SARS-CoV-2 and myelin oligodendrocyte glycoprotein (MOG). We discuss about capacity of SARS-CoV-2 to cause optic neuritis and possible significance of MOG antibodies in similar cases.

Indexed as

MOG antibodiesoptic neuritisSARS-CoV-2

Identifiers

PMID34079389
PMCPMC8165557
OpenAlexW3165133781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.