ArticleInternational journal of general medicine2021
Identification of Brain Regions with Enhanced Functional Connectivity with the Cerebellum Region in Children with Attention Deficit Hyperactivity Disorder: A Resting-State fMRI Study.
Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 14 citations in OpenAlex.
- Sexual Dimorphisms in Neurodevelopment May Affect TBI Recovery in Pediatric Patients.Biomedicines · 2025Review
- Abnormal stability of dynamic functional architecture in drug-naïve children with attention-deficit/hyperactivity disorder.BMC psychiatry · 2024Article
- Behaviour-correlated profiles of cerebellar-cerebral functional connectivity observed in independent neurodevelopmental disorder cohorts.Translational psychiatry · 2024Article
- Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model.Communications biology · 2023Article
- Disrupted structural connectivity and less efficient network system in patients with the treatment-naive adult attention-deficit/hyperactivity disorder.Frontiers in psychiatry · 2023Article
- Centrality and interhemispheric coordination are related to different clinical/behavioral factors in attention deficit/hyperactivity disorder: a resting-state fMRI study.Brain imaging and behavior · 2022Article
- Transfer learning in high-dimensional semiparametric graphical models with application to brain connectivity analysis.Statistics in medicine · 2022Article
- Effects of theFrontiers in psychiatry · 2021Article
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Authors and funding
2 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTo explore the brain regions with higher functional connectivity with the cerebellum at resting state and the brain functions related to cognitive function in children with attention-deficit hyperactivity disorder (ADHD).
methodsThirty children with ADHD and 33 typically developing children (TDC) were examined using resting-state functional magnetic resonance imaging (fMRI) scans. Seed-based functional connectivity (FC) analysis was performed.
resultsFour brain areas with higher FC values were identified in ADHD children. These four areas were the left middle frontal gyrus, right middle frontal gyrus, right superior temporal gyrus and left parahippocampal gyrus (P < 0.05). The results of the CPT show that the number of omission errors was significantly higher in the children with ADHD than in the TD group (5.13±5.12 vs 2.18±2.36, P = 0.000). The commission number in the ADHD group was also significantly higher than that of the TD group (4.03±6.56 vs 2.00±2.85, P = 0.002). However, no statistically significant difference was observed in the correct reaction time between the two groups (641.54±146.79 ms vs 584.81±145.82 ms, P = 0.835).
conclusionThe dysfunction of cerebellar functional connectivity in specific brain regions may be one of the pathological and physiological causes of cognitive impairment of ADHD.
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