Evidence map›Paper›PMID 34079305›Full record

ArticleInfection and drug resistance2021

Investigation and Analysis of the Colonization and Prevalence of Carbapenem-Resistant

Yan Sun, Lixin Yu, Wei Gao, Jinzhen Cai, Wentao Jiang, Wei Lu, Yihe Liu, Hong Zheng

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Risk factors, and outcomes of patients with carbapenem-resistantFrontiers in cellular and infection microbiology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yan SunOrgan Transplantation Center, Tianjin First Central Hospital, Tianjin, 300192, People's Republic of China.
Lixin YuOrgan Transplantation Center, Tianjin First Central Hospital, Tianjin, 300192, People's Republic of China.
Wei GaoOrgan Transplantation Center, Tianjin First Central Hospital, Tianjin, 300192, People's Republic of China.
Jinzhen CaiOrgan Transplantation Center, Tianjin First Central Hospital, Tianjin, 300192, People's Republic of China.
Wentao JiangOrgan Transplantation Center, Tianjin First Central Hospital, Tianjin, 300192, People's Republic of China.
Wei LuLiver Cancer Treatment Centre, Tianjin Medical University Cancer Institute and Hospital, Tianjin, People's Republic of China.
Yihe LiuOrgan Transplantation Center, Tianjin First Central Hospital, Tianjin, 300192, People's Republic of China.
Hong ZhengOrgan Transplantation Center, Tianjin First Central Hospital, Tianjin, 300192, People's Republic of China.
Tianjin People's Hospital · CNTianjin First Center Hospital · CNTianjin Medical University · CNTianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the colonization and prevalence of carbapenem-resistant

methodsA prospective study involving 152 pediatric patients undergoing liver transplantation was carried out. Anal swab bacteria cultures were collected when the patients entered the intensive care unit (ICU) and when they left in order to screen for intestinal CRE colonization. The results were grouped according to the occurrence of CRE infection following surgery, and the patients were divided into two groups: a CRE infection group and a non-CRE infection group. Univariate analysis and multiple logistic regression analysis were conducted to determine the independent risk factors of CRE infection and analyze the survival rate.

resultsOf the 152 pediatric liver transplant recipients enrolled in the study, there were 13 cases of postoperative CRE infection and 139 cases of non-CRE infection. The incidence of preoperative CRE infection, preoperative cytomegalovirus (CMV) infection, and preoperative sepsis in the CRE infection group was significantly higher than in the non-CRE infection group (

conclusionThe independent risk factors of CRE infection following pediatric liver transplantation include preoperative CRE infection and pre-ICU CRE colonization. CRE infection progresses quickly, with a poor prognosis and a high mortality rate. The CRE screening of anal swabs is crucial for the early detection of CRE infection.

Indexed as

anal swabscarbapenem-resistant EnterobacteriaceaeCRECT screeningintestinal colonizationliver transplantation

Identifiers

PMID34079305
PMCPMC8164869
OpenAlexW3165082924

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.