Evidence map›Paper›PMID 34079301›Full record

ArticleInfection and drug resistance2021

Landscape of Multidrug-Resistant Gram-Negative Infections in Egypt: Survey and Literature Review.

Amani El-Kholy, Hadir A El-Mahallawy, Noha Elsharnouby, Mohamed Abdel Aziz, Ahmed Mohamed Helmy, Ramy Kotb

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Amani El-KholyDepartment of Clinical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID 0000-0002-0645-7664
Hadir A El-MahallawyClinical Pathology Department, National Cancer Institute, Cairo University, Cairo, Egypt.ORCID 0000-0003-2887-8125
Noha ElsharnoubyDepartment of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Mohamed Abdel AzizPfizer Egypt, Levant & Iraq Medical Affairs, Cairo, Egypt.
Ahmed Mohamed HelmyPfizer Egypt Medical Affairs, Cairo, Egypt.
Ramy KotbPfizer Africa & Middle East Medical Affairs, Dubai, United Arab Emirates.
Cairo University · EGAin Shams University · EGWorld Health Organization - Egypt · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis article is the first to review published reports on the prevalence of multidrug-resistant (MDR) gram-negative infections in Egypt and gain insights into antimicrobial resistance (AMR) surveillance and susceptibility testing capabilities of Egyptian medical centers. MATERIALS AND

methodsA literature review and online survey were conducted.

resultsThe online survey and literature review reported high prevalence of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (19-85.24% of

conclusionThis survey has highlighted the presence of knowledge gaps as well as limitations in the surveillance and monitoring capabilities of AMR in Egypt, with most laboratories lacking rapid diagnostics and molecular testing. Future efforts in Egypt should focus on tackling these issues via nationwide initiatives, including understanding the AMR trends in the country, capacity building of laboratories and their staff to correctly and timely identify AMR, and introducing newer antimicrobials for targeting emerging resistance mechanisms in Gram-negative species.

Indexed as

EgyptGram-negative bacteriahospital-acquired pneumoniaintra-abdominal infectionsmultidrug resistanceurinary tract infections

Identifiers

PMID34079301
PMCPMC8163635
OpenAlexW3165125948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.