ArticleAnnals of dermatology2021
Efficacy and Safety of Treatment with Fractional 1,064-nm Picosecond Laser with Diffractive Optic Element for Wrinkles and Acne Scars: A Clinical Study.
Article in Annals of dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Comparative Efficacy and Safety of 1064-nm Picosecond Laser and 1927-nm Fractional Thulium Laser for Atrophic Acne Scars in Asian Patients: A Prospective, Randomized, Split-Face Study.Lasers in surgery and medicine · 2026Trial
- The Comparison of the Efficacy and Safety of Fractional 1064 nm Nd:YAG Picosecond Laser and Fractional Q-Switched 1064-nm Nd:YAG Laser in the Improvement of Photoaging: A Split-Face Study.Journal of cosmetic dermatology · 2025Article
- Emerging Innovations in Acne Management: A Focus on Non-Pharmacological Therapeutic Devices.Journal of Korean medical science · 2025Review
- Novel Application of 1064-nm Picosecond Nd:YAG Laser for Male Androgenetic Alopecia Treatment.The Journal of clinical and aesthetic dermatology · 2024Article
- Diffractive micro-lens array (DLA) for uniform and selective picosecond laser treatment.Biomedical optics express · 2023Article
- Truncal Acne and Scarring: A Comprehensive Review of Current Medical and Cosmetic Approaches to Treatment and Patient Management.American journal of clinical dermatology · 2023Review
- Article
- Comparison of 1064-nm Nd:YAG picosecond laser using fractional micro-lens array vs. ablative fractional 2940-nm Er:YAG laser for the treatment of atrophic acne scar in Asians: a 20-week prospective, randomized, split-face, controlled pilot study.Frontiers in medicine · 2023Article
- In Vivo Identification of Skin Photodamage Induced by Fractional CODiagnostics (Basel, Switzerland) · 2022Article
- Dermatology: how to manage acne vulgaris.Drugs in context · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFractional picosecond lasers is effective for the treatment of wrinkles or acne scars.
objectiveTo investigate the safety and efficacy of treatment with a fractional 1,064-nm picosecond laser with a diffractive optic element for facial wrinkles and acne scars.
methodsThis prospective open-labeled trial comprised 22 subjects with facial wrinkles or acne scars. Subjects received three laser treatments with a fractional 1,064-nm picosecond laser at 3-week intervals. The efficacy and safety were evaluated at every visit and 2 months after the final treatment (14 weeks from the first treatment session). Global photographic assessments were performed by three blinded dermatologists and the subjects. Skin profilometry was performed using three-dimensional digital photographs; viscoelasticity was measured.
resultsThe overall mean global improvement scores assessed by the dermatologists at weeks 3, 6, and 14, were 1.8±1.46, 2.5±1.88, and 3.5±1.84, respectively, and those assessed by the subjects were 2.7±2.08, 4.1±2.24, and 5.0±2.52, respectively. Skin profilometry showed significant improvements in the skin wrinkles, texture, depressions, and pores. The gross elasticity and skin firmness significantly improved by 10.96% and 9.04%, respectively. The major adverse reactions were erythema, pruritus, and petechiae, which disappeared within 2~3 days.
conclusionThe fractional 1,064-nm picosecond laser is an effective and safe therapeutic modality for skin rejuvenation.
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