Evidence map›Paper›PMID 34079023›Full record

ArticleScientific reports2021

Circulation derived from 4D flow MRI correlates with right ventricular dysfunction in patients with tetralogy of Fallot.

Nanae Tsuchiya, Michinobu Nagao, Yumi Shiina, Shohei Miyazaki, Kei Inai, Sadayuki Murayama, Shuji Sakai

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Increased Diastolic Energy Loss Associated with Cardiac Events in Adults with Pulmonary Atresia Suffering from Intact Ventricular Septum.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  3. Article
  4. Article
  5. Wall shear stress in outflow tract premature ventricular contraction location assessed through 4D-flow MRI.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  6. Article
  7. Article
  8. 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nanae TsuchiyaDepartment of Radiology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan.ORCID 0000-0003-2556-8287
Michinobu NagaoDepartment of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, 8-1 Wakamatsu Kawada, Tokyo, 1628666, Japan. nagao.michinobu@twmu.ac.jp.ORCID 0000-0001-6049-8857
Yumi ShiinaDepartment of Pediatric Cardiology, Division of Clinical Research for ACHD, Tokyo Women's Medical, Tokyo, Japan.
Shohei MiyazakiCardio Flow Design Inc., Tokyo, Japan.
Kei InaiDepartment of Pediatric Cardiology, Division of Clinical Research for Adult Congenital Heart Disease, Tokyo Women's Medical University, Tokyo, Japan.
Sadayuki MurayamaDepartment of Radiology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan.
Shuji SakaiDepartment of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, 8-1 Wakamatsu Kawada, Tokyo, 1628666, Japan.
Tokyo Women's Medical University · JPUniversity of the Ryukyus · JPSt. Luke's International Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We used 4D-flow MRI to investigate circulation, an area integral of vorticity, in the main pulmonary artery (MPA) as a new hemodynamic parameter for assessing patients with a repaired Tetralogy of Fallot (TOF). We evaluated the relationship between circulation, right ventricular (RV) function and the pulmonary regurgitant fraction (PRF). Twenty patients with a repaired TOF underwent cardiac MRI. Flow-sensitive 3D-gradient sequences were used to obtain 4D-flow images. Vortex formation in the MPA was visualized, with short-axis and longitudinal vorticities calculated by software specialized for 4D flow. The RV indexed end-diastolic/end-systolic volumes (RVEDVi/RVESVi) and RV ejection fraction (RVEF) were measured by cine MRI. The PR fraction (PRF) and MPA area were measured by 2D phase-contrast MRI. Spearman ρ values were determined to assess the relationships between circulation, RV function, and PRF. Vortex formation in the MPA occurred in 15 of 20 patients (75%). The longitudinal circulation (11.7 ± 5.1 m

Indexed as

AdolescentAdultCardiac Surgical ProceduresChildFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesPulmonary ArteryPulmonary Valve InsufficiencyStroke VolumeTetralogy of FallotVentricular Dysfunction, Right

Identifiers

PMID34079023
PMCPMC8172849
OpenAlexW3164757976

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.