Evidence map›Paper›PMID 34079019›Full record

ArticleScientific reports2021

Comparison between male and female breast cancer survival using propensity score matching analysis.

Serena Scomersi, Fabiola Giudici, Giuseppe Cacciatore, Pasquale Losurdo, Stefano Fracon, Sara Cortinovis, Rita Ceccherini, Fabrizio Zanconati, Maura Tonutti, Marina Bortul

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Elucidating Sex-Specific Immune Profiles in a Breast Cancer Model.International journal of molecular sciences · 2024
    Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Article
  18. Cancers · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Serena ScomersiAzienda Sanitaria Universitaria Giuliano Isontina, ASUGI, SSD Breast Unit, Cattinara Hospital, Strada di Fiume 447, 34129, Trieste, Italy. Serena.scomersi@asugi.sanita.fvg.it.
Fabiola GiudiciUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Via Loredan, 18, 35131, Padua, Italy.
Giuseppe CacciatoreDepartment of Medical, Surgical and Health Sciences, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34129, Trieste, Italy.
Pasquale LosurdoDepartment of Medical, Surgical and Health Sciences, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34129, Trieste, Italy.
Stefano FraconDepartment of Medical, Surgical and Health Sciences, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34129, Trieste, Italy.
Sara CortinovisDepartment of Medical, Surgical and Health Sciences, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34129, Trieste, Italy.
Rita CeccheriniAzienda Sanitaria Universitaria Giuliano Isontina, ASUGI, SSD Breast Unit, Cattinara Hospital, Strada di Fiume 447, 34129, Trieste, Italy.
Fabrizio ZanconatiAzienda Sanitaria Universitaria Giuliano Isontina, ASUGI, SSD Breast Unit, Cattinara Hospital, Strada di Fiume 447, 34129, Trieste, Italy.
Maura TonuttiAzienda Sanitaria Universitaria Giuliano Isontina, ASUGI, SSD Breast Unit, Cattinara Hospital, Strada di Fiume 447, 34129, Trieste, Italy.
Marina BortulAzienda Sanitaria Universitaria Giuliano Isontina, ASUGI, SSD Breast Unit, Cattinara Hospital, Strada di Fiume 447, 34129, Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male breast cancer (MBC) is a rare disease. The few studies on MBC reported conflicting data regarding survival outcomes compared to women. This study has two objectives: to describe the characteristics of a single-cohort of MBC and to compare overall survival (OS) and disease-free survival (DFS) between men and women using the propensity score matching (PSM) analysis. We considered MBC patients (n = 40) diagnosed between January 2004 and May 2019. Clinical, pathological, oncological and follow-up data were analyzed. Univariate analysis was performed to determine the prognostic factors on OS and DFS for MBC. We selected female patients with BC (n = 2678). To minimize the effect of the imbalance of the prognostic factors between the two cohorts, the PSM method (1:3 ratio) was applied and differences in survival between the two groups were assessed. The average age of MBC patients was 73 years. The 5-year OS and DFS rates were 76.7% and 72.2% respectively. The prognostic factors that significantly influenced OS and DFS were tumor size and lymph node status. After the PSM, 5 year-OS was similar between MBC and FBC (72.9% vs 72.3%, p = 0.70) while we found a worse DFS for MBC (72.2% vs 91.4%, p  = 0.03). Our data confirmed previous reported MBC characteristics: we found a higher risk of recurrence in MBC compared to FMC but similar OS. MBC and FMC are different entities and studies are needed to understand its epidemiology and guide its management.

Indexed as

AgedAged, 80 and overBreast NeoplasmsBreast Neoplasms, MaleFemaleHumansLymph NodesMaleMiddle AgedNeoplasm GradingNeoplasm Recurrence, LocalNeoplasm StagingPrognosisPropensity ScoreRetrospective StudiesRisk Assessment

Identifiers

PMID34079019
PMCPMC8172634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.