ArticleScientific reports2021
Risk factors for the severity of Guillain-Barré syndrome and predictors of short-term prognosis of severe Guillain-Barré syndrome.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Guidelines for Neuroprognostication in Adults with Guillain-Barré Syndrome.Neurocritical care · 2023Guideline
- Prognostic Nutritional Index as a Biomarker of Disease Severity and Long-Term Outcome in Guillain-Barré Syndrome.Journal of the peripheral nervous system : JPNS · 2025Observational
- A retrospective observational study of clinical and electrophysiological types of Guillain-Barre syndrome from Delhi.Journal of family medicine and primary care · 2025Article
- Guillain-Barré syndrome (GBS) after severe/critical COVID-19 or COVID-19 vaccination.European journal of medical research · 2025Article
- Predictors of the Short-Term Outcomes of Guillain-Barré Syndrome: Exploring Electrodiagnostic and Clinical Features.Brain and behavior · 2025Article
- Malnutrition and nutritional deficits as aggravating factors in Guillain-Barré Syndrome: a call for nutritional intervention in the Gaza Strip.Frontiers in public health · 2025Article
- Prognostic factors of mechanical ventilation in Guillain-Barré syndrome among adults and children in Vietnam.Clinical neurophysiology practice · 2025Article
- Clinical Characteristics and Prognosis of ICU-Admitted Patients with Guillain-Barre Syndrome: A Report from a Large Teaching Hospital in South Iran.Iranian journal of medical sciences · 2024Article
- Incidence of Cardiovascular Instability in Patients With Guillain-Barré Syndrome: A Retrospective Study.Cureus · 2024Article
- Clinical predictors for mechanical ventilation assistance in Guillain-Barré syndrome.Frontiers in neurology · 2024Article
- Interpretable Machine Learning Model for Predicting the Prognosis of Guillain-Barré Syndrome Patients.Journal of inflammation research · 2024Article
- An Analysis of Respiratory Muscle Paralysis of Adult Patients in Guillain-Barré Syndrome: A Retrospective Analysis.Medicina (Kaunas, Lithuania) · 2023Article
- Neutrophil-lymphocyte ratio in Guillain-Barré syndrome: A prognostic biomarker of severe disease and mechanical ventilation in Bangladesh.Journal of the peripheral nervous system : JPNS · 2023Article
- An unusual occurrence of opsoclonus and liver enzymes elevation in a patient with acute motor and sensory axonal neuropathy subtype of Guillain-Barré syndrome.BMC neurology · 2022Article
- Article
- Case Report: Delayed Guillain-Barré syndrome following trauma: A case series and manage considerations.Frontiers in surgery · 2022Article
- Neurologic complications of coronavirus and other respiratory viral infections.Handbook of clinical neurology · 2022Review
- Clinical Features and Outcome of the Guillain-Barre Syndrome: A Single-Center 11-Year Experience.Frontiers in neurology · 2022Article
- Outcome of Guillain-Barré Syndrome (GBS) During Peripartum Period: A Hospital-Based Observational Study.Annals of Indian Academy of NeurologyArticle
- Disease-specific divergence of inflammatory and metabolic biomarkers in neurocritical neuromuscular disorders.Frontiers in neurologyArticle
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Guillain-Barré syndrome (GBS) is a neurological disorder characterized by paralysis. Identifying the severity, appropriate therapeutic method, and prognosis of GBS at an early stage is highly important. This study aimed to investigate the modifiable risk factors for the severity of GBS and consequent need for mechanical ventilation (MV) and to identify clinical predictive factors for poor short-term outcomes of severe GBS. 155 GBS patients who were admitted to the Affiliated Yantai Yuhuangding Hospital of Qingdao University during 2014-2020 were enrolled. Demographic, clinical, therapeutic and evolutionary data were collected and were then analyzed using univariate and multivariate regression analyses. Our analytic data demonstrated that the significant clinical predictors of severe GBS were recent history of surgery, older age, cranial nerve impairment, and elevated levels of liver enzymes (p < 0.05). Furthermore, autonomic dysfunction, lower Medical Research Council (MRC) score at nadir, and elevated levels of liver enzymes were significantly associated with MV for severe GBS (p < 0.05), and lower MRC score at nadir and autonomic dysfunction remained significant predictors of MV in severe GBS (p < 0.05). Lastly, recent history of surgery, lower MRC score at admission and at nadir, requirement for MV, and pneumonia during hospitalization were significantly associated with the short-term outcome of severe GBS and that lower MRC score at admission and need for MV were confirmed to be predictors of poor short-term prognosis (p < 0.05). Of note, this study suggested that recent history of surgery is a predictor of severity in GBS patients and is associated with the poor short-term prognosis of severe GBS.
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