Evidence map›Paper›PMID 34078960›Full record

ArticleScientific reports2021

Isotonic quadriceps endurance is better associated with daily physical activity than quadriceps strength and power in COPD: an international multicentre cross-sectional trial.

Erik Frykholm, Sarah Gephine, Didier Saey, Arthur Lemson, Peter Klijn, Eline Bij de Vaate, François Maltais, Hieronymus van Hees, André Nyberg

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effects of exercise on muscle fatigability in COPD: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Erik Frykholm *Department of Community Medicine and Rehabilitation, Physiotherapy, Umeå University , Umeå, Sweden. erik.frykholm@umu.se.
Sarah Gephine *Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Quebec, Canada.
Didier SaeyInstitut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Quebec, Canada.
Arthur LemsonDepartment of Pulmonary Diseases, Radboud UMC, Nijmegen, The Netherlands.
Peter KlijnDepartment of Pulmonary Rehabilitation, Merem Medical Rehabilitation, Hilversum, The Netherlands.
Eline Bij de VaateDepartment of Pulmonary Rehabilitation, Merem Medical Rehabilitation, Hilversum, The Netherlands.
François MaltaisInstitut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Quebec, Canada.
Hieronymus van HeesDepartment of Pulmonary Diseases, Radboud UMC, Nijmegen, The Netherlands.
André NybergDepartment of Community Medicine and Rehabilitation, Physiotherapy, Umeå University , Umeå, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knowledge about modifiable determinants of daily physical activity (PA) in patients with chronic obstructive pulmonary disease (COPD) is crucial to design effective PA interventions. The present study aimed to determine the contribution of quadriceps strength, power and endurance to daily PA in COPD. Additionally, for quadriceps endurance, we also aimed to determine to what extent the association varies according to the mode of movement (isotonic, isometric, or isokinetic). Using a multicentre cross-sectional trial design we determined the contribution of quadriceps function to daily PA (steps, sedentary time and time spent doing moderate-to-very-vigorous physical activity [MVPA]) using bivariate and partial Pearson correlation analysis (r) and multiple linear regression models (ΔR

Indexed as

ExerciseAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedMuscle ContractionPulmonary Disease, Chronic ObstructiveQuadriceps MuscleRespiratory Function Tests

Identifiers

PMID34078960
PMCPMC8172909

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.