Evidence map›Paper›PMID 34078916›Full record

ArticleNPJ systems biology and applications2021

Systems modeling predicts that mitochondria ER contact sites regulate the postsynaptic energy landscape.

A Leung, D Ohadi, G Pekkurnaz, P Rangamani

Open access · goldAbstract read
In one paragraph

Article in NPJ systems biology and applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Mitochondrial morphology governs ATP production rate.The Journal of general physiology · 2023
    Article
  14. Article
  15. Mitochondria as central hubs in synaptic modulation.Cellular and molecular life sciences : CMLS · 2023
    Review
  16. Article
  17. Dynamic Regulation of Mitochondrial [CaInternational journal of molecular sciences · 2022
    Article
  18. Article
  19. Morphological principles of neuronal mitochondria.The Journal of comparative neurology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A Leung *Chemical Engineering Graduate Program, University of California San Diego, La Jolla, CA, USA.
D Ohadi *Department of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, CA, USA.
G PekkurnazNeurobiology Section, Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-7388-6178
P RangamaniDepartment of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, CA, USA. padmini.rangamani@eng.ucsd.edu.ORCID 0000-0001-5953-4347
University of California San Diego · US

Funding

Metabolic Regulation of Mitochondrial FunctionR35GM128823 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Gulcin Pekkurnaz · 2018 to 2026
$4.1M
NIGMS NIH HHS R35 GM128823
6 · The paper itself

Abstract

Spatiotemporal compartmentation of calcium dynamics is critical for neuronal function, particularly in postsynaptic spines. This exquisite level of Ca

Indexed as

Endoplasmic ReticulumMitochondrial MembranesCalciumCytosolMitochondriaCalcium

Identifiers

PMID34078916
PMCPMC8172538
OpenAlexW3164234422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.