Evidence map›Paper›PMID 34078754›Full record

ArticleThe Journal of veterinary medical science2021

Histological comparison of malignant epithelioid mesothelioma in young and adult cattle.

Yuuto Kawashima, Ayako Fujimoto, Morihiro Saito, Osamu Mikami, Yoshiharu Ishikawa, Koichi Kadota

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Pleural mesothelioma in a California sea lion (Zalophus californianus).The Journal of veterinary medical science · 2023
    Article
  2. Biphasic pleural mesothelioma in a goat.The Canadian veterinary journal = La revue veterinaire canadienne · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yuuto KawashimaSorachi Livestock Hygiene Service Center, 12-37 Okayamacho, Iwamizawa, Hokkaido 079-0181, Japan.
Ayako FujimotoHidaka Livestock Hygiene Service Center, 2-88-5 Shizunai-asahicho, Shinhidaka, Hokkaido 056-0003, Japan.
Morihiro SaitoCollege of Nutritional Science, Kagawa Nutrition University, 3-9-21 Chiyoda, Sakado, Saitama 350-0288, Japan.
Osamu MikamiHokkaido Research Station, National Institute of Animal Health, National Agriculture and Food Research Organization, 4 Hitsujigaoka, Toyohira, Sapporo, Hokkaido 062-0045, Japan.
Yoshiharu IshikawaHokkaido Research Station, National Institute of Animal Health, National Agriculture and Food Research Organization, 4 Hitsujigaoka, Toyohira, Sapporo, Hokkaido 062-0045, Japan.
Koichi KadotaHokkaido Research Station, National Institute of Animal Health, National Agriculture and Food Research Organization, 4 Hitsujigaoka, Toyohira, Sapporo, Hokkaido 062-0045, Japan.
Hokkaido Agricultural Research Center · JPMatsumoto Livestock Hygiene Service Center · JPKagawa Nutrition University · JPNational Agriculture and Food Research Organization · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The histology and immunohistochemistry of pleomorphic and conventional epithelioid mesotheliomas were examined. The former was detected in two young calves aged 2 and 4 months and was characterized by pleomorphic and atypical cells with decreased expression of cytokeratin 7 (CK7). In contrast, the latter was found in a 31-month-old heifer, consisting of tumor cells uniform in size and shape with CK7 expression in nearly all cells. Production of collagen by tumor cells was demonstrated in both histological types, and was considered to be characteristic of bovine epithelioid mesothelioma. Pleomorphic mesothelioma is far more pleomorphic and mitotically active than conventional mesothelioma, and its normal counterpart may be immature mesothelial cells with high proliferation potential, which exist in fetal life and early calfhood.

Indexed as

Cattle DiseasesLung NeoplasmsMesotheliomaMesothelioma, MalignantAnimalsBiomarkers, TumorCattleDiagnosis, DifferentialFemaleImmunohistochemistryBiomarkers, Tumorcattlecollagen productioncytokeratin 7epithelioid mesotheliomapleomorphic mesothelioma

Identifiers

PMID34078754
PMCPMC8267194
OpenAlexW3164795457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.