Evidence map›Paper›PMID 34078727›Full record

ArticleSaudi medical journal2021

Transperineal versus transrectal multi-parametric magnetic resonance imaging fusion targeted prostate biopsy.

Danny Rabah, Waleed Al-Taweel, Farrukh Khan, Mostafa Arafa, Shahbaz Mehmood, Alaa Mokhtar, Karim Farhat

Abstract read
In one paragraph

Article in Saudi medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Danny RabahFrom the Department of Surgery (Rabah, Khan), College of Medicine; from the Cancer Research Chair (Rabah, Arafa, Farhat), King Saud University, and from the Department of Urology (Rabah, Al-Taweel, Mokhtar), King Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Waleed Al-TaweelFrom the Department of Surgery (Rabah, Khan), College of Medicine; from the Cancer Research Chair (Rabah, Arafa, Farhat), King Saud University, and from the Department of Urology (Rabah, Al-Taweel, Mokhtar), King Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Farrukh KhanFrom the Department of Surgery (Rabah, Khan), College of Medicine; from the Cancer Research Chair (Rabah, Arafa, Farhat), King Saud University, and from the Department of Urology (Rabah, Al-Taweel, Mokhtar), King Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Mostafa ArafaFrom the Department of Surgery (Rabah, Khan), College of Medicine; from the Cancer Research Chair (Rabah, Arafa, Farhat), King Saud University, and from the Department of Urology (Rabah, Al-Taweel, Mokhtar), King Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Shahbaz MehmoodFrom the Department of Surgery (Rabah, Khan), College of Medicine; from the Cancer Research Chair (Rabah, Arafa, Farhat), King Saud University, and from the Department of Urology (Rabah, Al-Taweel, Mokhtar), King Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Alaa MokhtarFrom the Department of Surgery (Rabah, Khan), College of Medicine; from the Cancer Research Chair (Rabah, Arafa, Farhat), King Saud University, and from the Department of Urology (Rabah, Al-Taweel, Mokhtar), King Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Karim FarhatFrom the Department of Surgery (Rabah, Khan), College of Medicine; from the Cancer Research Chair (Rabah, Arafa, Farhat), King Saud University, and from the Department of Urology (Rabah, Al-Taweel, Mokhtar), King Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare transperineal biopsies (TPBx) with transrectal ultrasound-guided biopsy (TRUSBx) in order to provide evidence, making clinicians able to select the appropriate biopsy approach under different conditions.

methodsA comparative prospective study, conducted in King Khalid University Hospital (KKUH) and King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Kingdom of Saudi Arabia, between March 2019 and February 2020. All patients with raised prostate-specific antigen or atypical digital rectal examination findings were subjected to multi-parametric magnetic resonance imaging (MRI). Those with positive findings were referred to targeted fusion- guided biopsy either TPBx or TRUSBx, randomly. Complication rate, cancer detection rate, and procedure time were recorded.

resultsTransperineal biopsies and TRUSBx had an equivalent complication rate. However, both case detection rate and clinically significant cancer detection rate were significantly higher in TPBx versus TRUSBx (45.1% versus 29.1%,

conclusionNo difference in complication rate was detected between the 2 procedures; however, TPBx was more effective for cancer detection in general and clinically significant cancer detection in particular.

Indexed as

Prostatic NeoplasmsHumansImage-Guided BiopsyMagnetic Resonance ImagingMaleProspective StudiesUltrasonography, Interventionalprostate cancer.Transperineal targeted biopsytransrectal targeted fusion biopsy

Identifiers

PMID34078727
PMCPMC9149710

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.